The origins and precolonial epidemiology of tuberculosis in the Americas: can we figure them out?
The origins and precolonial epidemiology of tuberculosis in the Americas: can we figure them out?
复制标题
美洲结核病的起源和前殖民流行病学：我们能弄清楚吗？
DOI：
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
T. M. Daniel
中科院分区：
文献类型：
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作者：
T. M. Daniel
回顾了殖民前美洲结核病的古生物学证据，以阐明其起源和随后的流行病学。分枝杆菌属是一个古老的属，结核分枝杆菌可能在20,400到15,300年前就已经分化了。美洲有来自亚洲的移民，经历了两次大迁徙，一次发生在2万多年前，另一次发生在12000到11000年前。结核病随着这些移民到达美洲，在分散的小人口群体中保持着较低的地方性。从大约1500年前开始，结核病开始流行，可能发生在南美洲的安第斯地区。在欧洲殖民时期，它没有及时到达或消退，没有留下高度敏感的美洲原住民。
Paleologic evidence of tuberculosis in the precolonial Americas is reviewed to cast light on its origins and subsequent epidemiology. The genus Mycobacterium is an ancient one, and M. tuberculosis may have differentiated 20,400 to 15,300 years ago. The Americas were peopled by migrants from Asia in two major migrations, one occurring more than 20,000 years ago and the other 12,000 to 11,000 years ago. Tuberculosis reached the Americas with these migrants, persisting at a low level of endemnicity in small, dispersed population groups. Beginning about 1500 years ago, an epidemic of tuberculosis began, probably in the Andean region of South America. It did not reach or subsided in time to leave highly susceptible indigenous American populations at the time of European colonization.