Initial dissolution rate studies on dental enamel after CO2 laser irradiation.
Initial dissolution rate studies on dental enamel after CO2 laser irradiation.
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CO2 激光照射后牙釉质的初始溶解率研究。
DOI：
10.1177/00220345920710070701
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发表时间：
1992
影响因子：
7.6
通讯作者：
Powell,GL
中科院分区：
文献类型：
--
作者：
Fox,JL;Yu,D;Otsuka,M;Higuchi,WI;Wong,J;Powell,GL
研究了CO2激光照射对人牙釉质溶解行为的影响。用 10.6 μm 的连续波 CO2 激光照射人体牙釉质，并通过旋转盘组件在 0.1 mol/L 醋酸盐缓冲液（pH = 4.5）（含或不含钙和/或磷酸盐共同离子）中测量初始溶解速率 (IDR)。还确定了不同水平的（1-羟基亚乙基）二膦酸（EHDP）、氟化物（F）和十二胺HCl（DAC）对IDR的影响。所有的发现都与 CO2 激光照射将牙釉质转化为具有位点 #2 特征的羟基磷灰石 (HAP) 的假设相一致 (Yamamoto 等人，1986)。发现激光照射后的溶解驱动力函数KHAP = aca10apO46aOH2 的值为10-129.9，而激光照射前的值为10-121.4。正如站点 #2 HAP 的预期，EHDP (3 mmol/L) 和 DAC (3 mmol/L) 的 IDR 值基本上为零。对于溶液F，推导的溶解驱动力函数KFAP=aca10aPO46aF2在激光照射后为10-128.6，与激光照射前相比为10-116.3。这些结果都支持以下假设：(1) 激光照射可以将人类牙釉质表面转化为磷灰石，其有效溶解度（即位点#2 HAP）明显低于未激光照射的牙釉质； (2) 激光治疗和这些化学溶解速率抑制剂之间存在显着的协同作用（再次与位点 #2 HAP 一致）。简单的模型计算表明，在存在和不存在氟化物的情况下，这些激光引起的溶解驱动力变化应显着降低牙釉质对口腔中可能遇到的酸挑战类型的敏感性
The influence of CO2laser irradiation on the dissolution behavior of human dental enamel has been investigated. Human enamel was irradiated by a continuous-wave CO2laser at 10.6 μm and initial dissolution rates (IDRs) were measured in 0.1 mol/L acetate buffer, pH = 4.5, both with and without calcium and/or phosphate common ion, by means of a rotating disk assembly. The effects of (1-hydroxyethylidene) bisphosphonic acid (EHDP), fluoride (F), and dodecylamine HCI (DAC) at various levels upon the IDR were also determined. All of the findings were consistent with the hypothesis that CO2laser irradiation converts dental enamel to hydroxyapatite (HAP) possessing site #2 character (Yamamotoet al.,1986). The dissolution driving force function, KHAP = aca10apO46aOH2, was found to have a value of 10-129.9after being lased, as compared with 10-121.4before being lased. The IDR values for EHDP (3 mmol/L) and DAC (3 mmol/L) were essentially zero as expected for site #2 HAP. For solution F, the deduced dissolution driving force function, KFAP= aca10aPO46aF2was 10-128.6after being lased as compared with 10-116.3before being lased. These results all support the hypotheses (1) that laser irradiation may convert the surface of human dental enamel to an apatite of significantly lower effective solubility (i.e., site #2 HAP) than that of unlased enamel; and (2) that there is significant synergism between laser treatment and these chemical dissolution rate inhibitors (again consistent with site #2 HAP).Simple model calculations indicate that, in both the presence and absence of fluoride, these laser-induced changes in the driving force for dissolution should dramatically lessen the susceptibility of enamel to the types of acid challenge that might be encountered in the mouth