Complexes with truncated RNAs from the large domain of Archaeoglobus fulgidus signal recognition particle.
Complexes with truncated RNAs from the large domain of Archaeoglobus fulgidus signal recognition particle.
复制标题
与来自古生球菌信号识别颗粒大域的截短 RNA 形成的复合物。
DOI：
10.1111/j.1574-6968.2001.tb10626.x
复制
发表时间：
2001
影响因子：
2.1
通讯作者：
Zwieb,C
中科院分区：
文献类型：
--
作者：
Bhuiyan,SH;Pakhomova,ON;Hinck,AP;Zwieb,C
Protein SRP19 is an important component of the signal recognition particle (SRP) as it promotes assembly of protein SRP54 with SRP RNA and recognizes a tetranucleotide loop. Structural features and RNA binding activities of SRP19 of the hyperthermophilic archaeonArchaeoglobus fulgiduswere investigated. An updated alignment of SRP19 sequences predicted three conserved regions and two α-helices. With Af-SRP RNA the Af-SRP54 protein assembled into anA. fulgidusSRP which remained intact for many hours. Stable complexes were formed between Af-SRP19 and truncated SRP RNAs, including a 36-residue fragment representing helix 6 ofA. fulgidusSRP RNA.
