Measurement of pleural pressure at low and high frequencies in normal rabbits.
Measurement of pleural pressure at low and high frequencies in normal rabbits.
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正常兔子低频和高频胸膜压的测量。
DOI：
10.1152/jappl.1987.63.3.1142
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Chang,HK
中科院分区：
文献类型：
--
作者：
Chartrand,DA;Ye,TH;Maarek,JM;Chang,HK
在8只气管切开的成年家兔仰卧位，我们采用导管尖端压阻式压力传感器测量食管压力（Pes），并评估Pes的变化是胸膜压力（Ppl）的变化的有效性。我们应用了阻塞试验，其中气管插管在自发吸气努力或体表振荡范围为3至50 Hz期间被阻塞。记录Pes与气道开放压（Pao）的关系。在所有情况下，Pes和Pao的变化幅度和相位几乎相同。我们的结论是，通过闭塞试验评价，导管尖端压力传感器放置在兔食管可以给足够的估计局部胸膜变化高达至少50 Hz。
In eight tracheotomized adult rabbits placed in the supine position, we employed a catheter-tip piezoresistive pressure transducer to measure esophageal pressure (Pes) and assessed the validity of taking the changes in Pes to be the changes in pleural pressure (Ppl). We applied an occlusion test in which the tracheal cannula was occluded during either spontaneous inspiratory efforts or body surface oscillations ranging from 3 to 50 Hz. The relationship between Pes and airway opening pressure (Pao) was recorded. In all instances, the changes in Pes and Pao were virtually identical in both amplitude and phase. We conclude that, as evaluated by the occlusion test, a catheter-tip pressure transducer placed in the esophagus of rabbits can give adequate estimation of local pleural changes up to at least 50 Hz.