Caspases: key mediators of apoptosis

Caspases: key mediators of apoptosis
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DOI:
10.1016/s1074-5521(98)90615-9
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发表时间:
1998-05-01
影响因子:
--
通讯作者:
Thornberry, NA
Thornberry, NA
中科院分区:
生物1区
文献类型:
--
作者:
Thornberry, NA

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最近的研究已经确定,caspase蛋白酶家族的成员是保守的细胞死亡程序的重要组成部分。对它们的生物学作用、结构和机制的深入了解使研究人员能够开始探索半胱天冬酶抑制剂的治疗潜力。
Recent studies have established that members of the caspase protease family are essential components of a conserved cell death program. Insights into their biological roles, structure and mechanism are enabling investigators to begin to explore the therapeutic potential of caspase inhibition.