Exposure of young children working on Mexican tobacco plantations to organophosphorous and carbamic pesticides, indicated by cholinesterase depression
Exposure of young children working on Mexican tobacco plantations to organophosphorous and carbamic pesticides, indicated by cholinesterase depression
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DOI：
10.1111/j.1365-2214.2006.00702.x
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发表时间：
2007-05-01
影响因子：
1.9
通讯作者：
Hesketh, T.
中科院分区：
文献类型：
--
作者：
Gamlin, J.;Romo, P. Diaz;Hesketh, T.
墨西哥纳亚里特州的烟草种植园大量使用有机磷和氨基农药，有多达3000名儿童及其家庭在那里工作。有机磷农药和氨基农药很容易通过皮肤吸入或吸收，儿童可能特别容易受到农药的影响，因为他们的体重较小，身高较低。更经常的手-口接触。本研究的目的是评估农药暴露对非常年轻的墨西哥烟草工人和弟弟妹妹的乙酰胆碱酯酶水平的影响。方法采集采收期间（暴露）160名0-14岁儿童和采收后6-9个月（基线）62名家庭社区儿童的血液样本。检测样品的胆碱酯酶，校正血红蛋白和环境温度。结果15%的儿童抑郁得分在基线水平的-40%到190%之间。33%的儿童抑郁得分至少为15%，86%的儿童贫血。结论幼儿在工作过程中暴露于具有潜在危害性和毒性的农药中。需要进一步的研究来评估这种接触对健康的实际急性和慢性影响。
Background Organophosphorous (OP) and carbamic pesticides are used in large quantities on tobacco plantations in Nayarit State, Mexico, where up to 3000 children and their families work. OP and carbamic pesticides are easily inhaled or absorbed through the skin and children may be particularly vulnerable to pesticides because of their smaller body mass, their height leaves.and more regular hand- mouth contact. The aim of this study is to assess the effect of pesticide exposure on acetylcholinesterase levels of very young migrant Mexican tobacco workers and younger siblings.Methods Blood samples were collected from 160 children aged 0-14 years during harvest (exposure) and from 62 children in their home communities 6-9 months after harvest (baseline). Samples were tested for cholinesterase corrected for haemoglobin and ambient temperature.Results Fifteen per cent of children had depression scores ranging from -40% to 190% of their baseline levels. Thirty-three per cent of children had depression scores of at least 15% and 86% of children were anaemic.Conclusion These results suggest that very young children are exposed to potentially harmful and toxic amounts of pesticides while working. Further research is needed to assess the actual acute and chronic health impacts of such exposures.