Factors alleviating metabolic syndrome via diet-induced weight loss with or without exercise in overweight Japanese women
Factors alleviating metabolic syndrome via diet-induced weight loss with or without exercise in overweight Japanese women
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DOI：
10.1016/j.ypmed.2009.01.013
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发表时间：
2009-04-01
影响因子：
5.1
通讯作者：
Tanaka, Kiyoji
中科院分区：
文献类型：
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作者：
Nakata, Yoshio;Okura, Tomohiro;Tanaka, Kiyoji
Objective.尽管基线体重减轻5%-10%与肥胖相关疾病的改善有关，但只有少数研究探讨了缓解代谢综合征（MS）的因素。本研究旨在确定改变超重日本女性MS组分的因素。在1999年至2006年期间，从茨木和千叶招募了323名年龄在24-67岁、体重指数在25-40 kg/m2之间且存在至少一种MS组分的日本女性。参与者参加了一个为期3个月的减肥计划，包括低热量饮食，有或没有运动。采用分类回归树（CART）分析方法，对影响MS组分的因素进行分析。在323名参与者中，有309人完成了减肥计划并被纳入分析中。CART分析显示，基线体重减轻8.1%足以改善MS的至少I组分。同样，生成腹部肥胖（基本因素：体重减轻>= 13.0%）、高血压（基本因素：基线年龄，体重减轻= 13.2%）改善的分类树。这些结果表明，适度减肥8%-13%有助于改善超重日本女性的MS成分。(C)2009 Elsevier Inc. All rights reserved.
Objective. Although a 5%-10% loss in the baseline weight has been associated with improvement in obesity-related disorders, only a few studies have explored the factors to alleviate metabolic syndrome (MS). This study aimed to determine the factors that alter MS components in overweight Japanese women.Methods. Between 1999 and 2006,323 Japanese women aged 24-67 with body mass indices of 25-40 kg/m(2) and the presence of at least 1 component of MS were recruited from Ibaraki and Chiba. The participants were enrolled in a 3-month weight-loss program with a low-calorie diet with or without exercise. The factors to alleviate MS components were explored using classification and regression tree (CART) analyses.Results. Of the 323 participants, 309 completed the weight-loss program and were included in the analyses. The CART analyses revealed that a weight reduction of 8.1% in baseline body weight was sufficient to improve at least I component of MS. Similarly, classification trees were generated for improvement in abdominal obesity (essential factor: >= 13.0% weight loss), hypertension (essential factor: baseline age, = 13.2% weight loss).Conclusion. These results suggest that moderate weight loss of 8%-13% contributes to improving the MS components in overweight Japanese women. (C) 2009 Elsevier Inc. All rights reserved.