PcircRNA_finder: a software for circRNA prediction in plants
PcircRNA_finder: a software for circRNA prediction in plants
复制标题
PcircRNA_finder：植物circRNA预测软件
DOI：
10.1093/bioinformatics/btw496
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发表时间：
2016-11-15
期刊：
影响因子：
5.8
通讯作者：
Fan, Longjiang
中科院分区：
文献类型：
--
作者：
Chen, Li;Yu, Yongyi;Fan, Longjiang
动机：最近的研究揭示了非编码环状RNA（circRNA）在控制细胞过程中的重要作用。由于植物和哺乳动物基因组组织的差异，使用为动物和人类开发的算法的circRNA预测程序的灵敏度和准确性在植物中表现不佳。结果如下：通过对拟南芥和水稻模拟和真实的rRNA-/RNAase R RNA-Seq数据的分析，建立了一个比find_circ和CIRCexplorer更灵敏的植物circRNA预测软件（PcircRNA_finder）。可用性和实施：http://ibi.zju.edu.cn/bioinplant/tools/manual.htm。联系方式：fanlj@zju.edu.cn补充信息：补充数据可从生物信息学在线网站获得。
Motivation: Recent studies reveal an important role of non-coding circular RNA (circRNA) in the control of cellular processes. Because of differences in the organization of plant and mammal genomes, the sensitivity and accuracy of circRNA prediction programs using algorithms developed for animals and humans perform poorly for plants. Results: A circRNA prediction software for plants (termed PcircRNA_finder) was developed that is more sensitive in detecting circRNAs than other frequently used programs (such as find_circ and CIRCexplorer), Based on analysis of simulated and real rRNA-/RNAase R RNA-Seq data from Arabidopsis thaliana and rice PcircRNA_finder provides a more comprehensive sensitive, precise prediction method for plants circRNAs. Availability and Implementation: http://ibi.zju.edu.cn/bioinplant/tools/manual.htm. Contact: fanlj@zju.edu.cn Supplementary information: Supplementary data are available at Bioinformatics online.