Effectiveness of strategic anthelmintic treatments in the control of gastrointestinal nematodes and Fasciola gigantica in cattle in Iringa region, Tanzania
Effectiveness of strategic anthelmintic treatments in the control of gastrointestinal nematodes and Fasciola gigantica in cattle in Iringa region, Tanzania
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DOI：
10.1007/s11250-008-9150-5
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发表时间：
2009-01-01
影响因子：
1.7
通讯作者：
Kassuku, A. A.
中科院分区：
文献类型：
--
作者：
Keyyu, J. D.;Kyvsgaard, N. C.;Kassuku, A. A.
采用纵向田间试验的方法，研究了策略驱虫药对牛胃肠道线虫和巨型片形吸虫的控制效果。随机选取3个大型奶牛场、4个传统奶牛场和9个小型奶牛场共167头6-18个月牛。每个养殖场选取动物进行耳标，按活重分为3组，处理如下：T4组每年4次，分别在雨季中期、雨末、旱季中期和旱季后期/雨季早期，施用阿苯达唑10% 10 mg/kg水剂。T2组施用阿苯达唑10%水剂，剂量为10 mg/kg，每年2次（雨季中期和旱季末/雨季早期）。UT组为未处理对照组。每个月采集粪便、血液和牧草样本，持续13个月。此外，在每个采样日期测量个体体重（BWT）。结果显示，与未处理对照组相比，2种和4种策略处理组的粪蛋计数（FEC）分别显著降低49.5%和62.3% （P < 0.001）。每年2次和4次策略处理显著降低了动物通过粪便排出片吸虫卵的比例，分别降低了30.6%和51.7% （P < 0.001）。试验结束时，1年处理2次和4次的动物分别比未处理的动物增重14.8 kg和17.7 kg （P < 0.05）。该管理系统对吸片吸虫粪便中吸片吸虫卵的传代率和堆积细胞体积有显著影响（P < 0.05）。每年两次战略治疗方案仅对控制胃肠道线虫有效。结果表明，每年4次战略治疗方案可有效控制胃肠道线虫和巨型赤霉病，并可改善体重。
A longitudinal field trial was conducted to determine the effectiveness of strategic anthelmintic treatments in the control of gastrointestinal (GI) nematodes and Fasciola gigantica in cattle. A total of 167 cattle (6-18 months) from three large-scale dairy farms, four traditional farms and nine small-scale dairy farms were randomly selected. The selected animals on each farm were ear tagged and allocated into three groups based on live weight and treated as follows: Group T4 was treated with albendazole 10% drench at 10 mg/kg four times a year (mid rainy, end of the rain, mid dry and late dry/early rainy season). Group T2 was treated with albendazole 10% drench at 10 mg/kg two times a year (mid rainy and late dry/early rainy season). Group UT remained as untreated control. Faecal, blood and pasture samples were taken every month for 13 months. In addition, individual body weight (BWT) was measured on every sampling date. Results showed that two and four strategic treatments significantly reduced faecal egg counts (FEC) by 49.5% and 62.3% respectively compared to untreated control animals (P < 0.001). Two and four strategic treatments per year significantly reduced the proportion of animals passing Fasciola eggs in faeces by 30.6% and 51.7% (P < 0.001), respectively. Animals treated two and four times a year significantly outgained untreated animals by 14.8 kg and 17.7 kg respectively at the end of the trial (P < 0.05). The management system had a significant effect on packed cell volume and the proportion of animals passing Fasciola eggs in faeces (P < 0.05). The programme of two strategic treatments per year was only effective in controlling GI nematodes. It is concluded that a programme of four strategic treatments per year was effective in controlling GI nematodes and F. gigantica and improved weight gain.