Lysosomal enzymes in the interphotoreceptor matrix: acid protease.
Lysosomal enzymes in the interphotoreceptor matrix: acid protease.
复制标题
光感受器间基质中的溶酶体酶：酸性蛋白酶。
作者：
A. Adler;K. J. Martin
对从成年牛眼视网膜和视网膜色素上皮(PE)中洗涤的光感受器间基质(IPM)进行了酸性蛋白酶的检测。在IPM中观察到相当大的酶活性--接近整个视网膜-IPM-PE功能单位酸性蛋白水解酶总量的十分之一。在靠近PE的基质部分，比活性要高得多。根据在IPM中发现的酸性水解酶的发现，讨论了PE细胞可能分泌溶酶体酶的可能性，以及在PE吞噬细胞之前，IPM可能开始了落盘消化过程。
Interphotoreceptor matrix (IPM), washed from the retina and retinal pigment epithelium (PE) of adult bovine eyes, was assayed for acid protease. Considerable enzyme activity was observed in the IPM--close to one-tenth of the total acid protease of the entire retina-IPM-PE functional unit. The specific activity was much higher in that part of the matrix near the PE. Based on the finding of an acid hydrolase in the IPM, the possibility is discussed that PE cells may secrete lysosomal enzymes and that the process of shed-disc digestion may begin in the IPM, prior to phagocytosis by the PE.