Factors affecting enrollment in literacy studies for English- and Spanish-speaking cancer patients.
Factors affecting enrollment in literacy studies for English- and Spanish-speaking cancer patients.
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影响英语和西班牙语癌症患者扫盲研究入学的因素。
DOI：
10.1002/sim.3259
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发表时间：
2008
影响因子：
2
通讯作者：
Hahn,ElizabethA
中科院分区：
文献类型：
--
作者：
Du,Hongyan;Valenzuela,Veronica;Diaz,Patricia;Cella,David;Hahn,ElizabethA
背景资料：Study participation bias can affect inertions about outcomes.Objective：The objective is to comparison characteristics of participants and non-participants of two literacy studies.Methods：在英语和西班牙语癌症患者中进行了两项关于识字和健康相关生活质量的研究。患者有一系列的读写能力，每个入组的患者收到20美元。结果：922名讲英语的患者进行了接触。在符合资格标准的651人中，420人（64.5%）入学。487名讲西班牙语的患者接受了治疗。在符合资格标准的455人中，414人被录取（91.0%）（p<0.001）。进行多重插补以插补缺失数据。多变量logistic回归显示，招募中心是预测西班牙语患者入组的唯一因素。年龄、教育程度和招募地点是讲英语患者的重要预测因素。使用完整数据的患者进行敏感性分析产生了类似的结果。结论：讲西班牙语的患者的入组率远远高于讲英语的患者，这对未来在这一服务不足的人群中进行研究是令人鼓舞的。一个重要的识字相关因素（教育）不影响西班牙语患者的入组，表明本研究不存在选择偏倚。招募贫困患者较多且门诊等待时间较长的研究中心的入组率较高，这表明货币补偿和时间可用性可能是研究参与的重要考虑因素。版权所有© 2008约翰威利父子有限公司。
Background: Study participation bias can affect inferences regarding outcomes.Objective: The objective is to compare characteristics of participants and non‐participants of two literacy studies.Methods: Two studies of literacy and health‐related quality of life were conducted in English‐ and Spanish‐speaking cancer patients. Patients had a range of literacy skills, and each enrolled patient received $20.Results: Nine hundred and twenty‐two English‐speaking patients were approached. Among the 651 who met eligibility criteria, 420 were enrolled (64.5 per cent). Four hundred and eighty‐seven Spanish‐speaking patients were approached. Among the 455 who met eligibility criteria, 414 were enrolled (91.0 per cent) (p<0.001). Multiple imputations were performed to impute missing data. Multivariable logistic regression revealed that recruiting site was the only factor predictive of enrollment in Spanish‐speaking patients. Age, education, and recruiting site were important predictors in English‐speaking patients. Sensitivity analysis using patients with complete data generated similar results.Conclusions: Spanish‐speaking patients enrolled at a much higher rate than English‐speaking patients, which is encouraging for future research in this underserved population. One important literacy‐related factor (education) did not affect enrollment in Spanish‐speaking patients, suggesting that there was no selection bias in this study. Recruiting sites with more indigent patients and long clinic waiting times had higher enrollment, suggesting that monetary compensation and time availability may be important considerations in study participation. Copyright © 2008 John Wiley & Sons, Ltd.