MAPPING OF THE EARLY NEURAL PRIMORDIUM IN QUAIL CHICK CHIMERAS .1. DEVELOPMENTAL RELATIONSHIPS BETWEEN PLACODES, FACIAL ECTODERM, AND PROSENCEPHALON
MAPPING OF THE EARLY NEURAL PRIMORDIUM IN QUAIL CHICK CHIMERAS .1. DEVELOPMENTAL RELATIONSHIPS BETWEEN PLACODES, FACIAL ECTODERM, AND PROSENCEPHALON
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DOI：
10.1016/0012-1606(85)90101-0
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发表时间：
1985-01-01
影响因子：
2.7
通讯作者：
LEDOUARIN, NM
中科院分区：
文献类型：
--
作者：
COULY, GF;LEDOUARIN, NM
将卵裂期前至3体期的前外侧神经脊和神经板相关区域的特定片段等时和等时地移植到雏鸡宿主体内。这导致了表面上正常的大脑和面部结构的发育，移植组织对这些结构的贡献可以通过鹌鹑核标记来观察。结果表明，前外侧神经脊内含有腺垂体和嗅觉基板的祖细胞，鼻腔、鼻甲内的浅外胚层和喙的浅外胚层的祖细胞。当神经脊线的适当区域参与到鹌鹑-雏鸡的替换中时，卵牙由移植物来源的细胞组成。与包含胎盘外胚层的脊区相邻的神经板区的移植显示，下丘脑的推定区域与腺垂体的区域是毗邻的。同样的观察也发生在嗅觉定位和端脑的底部，嗅球后来是从端脑发育而来的。
Defined fragments of the anterolateral neural ridge and of the associated region of the neural plate of presomitic to 3-somite stage quail embryos were grafted isotopically and isochronically into chick hosts. This resulted in the development of apparently normal brain and facial structures to which the contribution of the grafted tissue could be observed by means of the quail nuclear marker. It was shown that the anterolateral neural ridge contains the progenitor cells of the adenohypophyseal and olfactory placodes and also of the superficial ectoderm lining the nasal cavity and conchae and the superficial ectoderm of the beak. When the appropriate region of the neural ridge was involved in the quail-chick substitution, the egg tooth was made up of graft-derived cells. Grafting of the neural plate area adjacent to the ridge territory containing the placodal ectoderm revealed that the presumptive region of the hypothalamus is contiguity with that of the adenohypophyseal placode. The same observation was made for the olfactory placode and the floor of the telencephalon from which the olfactive bulb later develops.