The effects of Compton camera data acquisition and readout timing on PG imaging for proton range verification.
The effects of Compton camera data acquisition and readout timing on PG imaging for proton range verification.
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DOI：
10.1109/trpms.2021.3057341
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发表时间：
2022-03
影响因子：
4.4
通讯作者：
Beddar, Sam
中科院分区：
文献类型：
--
作者：
Polf, Jerimy C.;Maggi, Paul;Panthi, Rajesh;Peterson, Stephen;Mackin, Dennis;Beddar, Sam
本研究的目的是确定康普顿相机 (CC) 的数据采集 (DAQ) 电子器件的特性如何影响临床质子束传输期间记录的瞬发伽马 (PG) 相互作用数据和重建图像的质量。我们使用蒙特卡罗加探测器效应 (MCDE) 模型来模拟 150 MeV 临床质子笔束向组织等效塑料模型的传递。通过 MCDE 模型，我们分析了当 CC 的 DAQ 电子器件的两个特性发生变化时，记录的 PG 交互数据如何变化：(1) 数据读出通道的数量； (2) 主动电荷收集、读出和复位时间。随着质子束剂量率的增加，对于 CC 当前的 DAQ 配置而言，记录的 PG 单、双和三散射事件的数量减少了 60 倍。然而，随着 DAQ 读出通道的增加和读出/重置时间的减少，在最高临床剂量率下记录的事件数量减少了 <5 倍。读出通道数量的增加和读出/重置时间的减少也导致了更高质量的记录数据。也就是说，记录的双散射和三散射中较高比例的是“真实”事件（由单个入射伽马引起），而不是“假”事件（由多个入射伽马引起）。记录数据数量和质量的增加使得即使在最高临床剂量率下也能重建更高质量的 PG 图像。
The purpose of this study was to determine how the characteristics of the data acquisition (DAQ) electronics of a Compton camera (CC) affect the quality of the recorded prompt gamma (PG) interaction data and the reconstructed images, during clinical proton beam delivery. We used the Monte-Carlo-plus-Detector-Effect (MCDE) model to simulate the delivery of a 150 MeV clinical proton pencil beam to a tissue-equivalent plastic phantom. With the MCDE model we analyzed how the recorded PG interaction data changed as two characteristics of the DAQ electronics of a CC were changed: (1) the number of data readout channels; and (2) the active charge collection, readout, and reset time. As the proton beam dose rate increased, the number of recorded PG single-, double-, and triple-scatter events decreased by a factor of 60× for the current DAQ configuration of the CC. However, as the DAQ readout channels were increased and the readout/reset timing decreased, the number of recorded events decreased by <5× at the highest clinical dose rate. The increased number of readout channels and reduced readout/reset timing also resulted in higher quality recorded data. That is, a higher percentage of the recorded double- and triple-scatters were “true” events (caused by a single incident gamma) and not “false” events (caused by multiple incident gammas). The increase in the number and the quality of recorded data allowed higher quality PG images to be reconstructed even at the highest clinical dose rates.
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影响因子：
3.5
作者：
Maggi P;Peterson S;Panthi R;Mackin D;Yang H;He Z;Beddar S;Polf J
通讯作者：
Polf J
影响因子：
3.8
作者：
Parodi K;Polf JC
通讯作者：
Polf JC
DOI：
10.1109/tns.2016.2622162
发表时间：
2017-01-01
影响因子：
4.4
作者：
Hueso-Gonzalez, F.;Pausch, G.;Enghardt, W.
通讯作者：
Enghardt, W.
影响因子：
1.3
作者：
Hueso-Gonzalez, F.;Golnik, C.;Pausch, G.
通讯作者：
Pausch, G.
影响因子：
3.8
作者：
Jan, Meei-Ling;Hsiao, Ing-Tsung;Huang, Hsuan-Ming
通讯作者：
Huang, Hsuan-Ming