OPTICAL-PROPERTIES OF INTRALIPID - A PHANTOM MEDIUM FOR LIGHT-PROPAGATION STUDIES
OPTICAL-PROPERTIES OF INTRALIPID - A PHANTOM MEDIUM FOR LIGHT-PROPAGATION STUDIES
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DOI：
10.1002/lsm.1900120510
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发表时间：
1992-01-01
影响因子：
2.4
通讯作者：
VANGEMERT, MJC
中科院分区：
文献类型：
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作者：
FLOCK, ST;JACQUES, SL;VANGEMERT, MJC
Intraperoid（TM）是一种静脉营养素，由磷脂胶束和水的乳液组成。由于Intraperoid是混浊的，在电磁光谱的可见光区域没有强吸收带，并且容易获得且相对便宜，因此它通常用作光剂量测定实验中的组织模拟体模介质。为了帮助调查人员需要一个可控的介质，在有限的波长范围内是光学等效的组织，我们已经编制了以前公布的值的光相互作用系数的Intraperoid，其中大部分是在633 nm的波长测量。我们已经扩大了测量的吸收和约化散射系数从460至690 nm和总衰减系数从500至890 nm。这些测量结果表明，对于10%英脱利匹特库存品，460和690 nm之间的吸收系数在0.015至0.001 cm-1之间变化，460和690 nm之间的减少散射系数在92至50 cm-1之间变化，总衰减系数在500和890 nm之间从575至150 cm-1变化，在460和690 nm之间，散射的平均余弦在0.87到0.82之间变化。有了这些数据，我们讨论了一个光学组织等效体模的设计，包括Intraperoid和黑色印度墨水。
Intralipid(TM) is an intravenous nutrient consisting of an emulsion of phospholipid micelles and water. Because Intralipid is turbid and has no strong absorption bands in the visible region of the electromagnetic spectrum, and is readily available and relatively inexpensive, it is often used as a tissue simulating phantom medium in light dosimetry experiments. In order to assist investigators requiring a controllable medium that over a finite range of wavelengths is optically equivalent to tissue, we have compiled previously published values of the optical interaction coefficients of Intralipid, most of which were measured at a wavelength of 633 nm. We have extended the measurements of the absorption and reduced scattering coefficients from 460 to 690 nm and the total attenuation coefficient from 500 to 890 nm. These measurements show that, for stock 10% Intralipid, the absorption coefficient varies from 0.015 to 0.001 cm-1 between 460 and 690 nm, the reduced scattering coefficient varies from 92 to 50 cm-1 between 460 and 690 nm, the total attenuation coefficient varies from 575 to 150 cm-1 between 500 and 890 nm, and the average cosine of scatter varies from 0.87 to 0.82 between 460 and 690 nm. With these data, we discuss the design of an optically tissue-equivalent phantom consisting of Intralipid and black India ink.