The regulatory switch of the muscle thin filament: Ca2+ or myosin heads?
The regulatory switch of the muscle thin filament: Ca2+ or myosin heads?
复制标题
肌肉细丝的调节开关：Ca2 还是肌球蛋白头？
DOI：
10.1007/bf00123476
复制
发表时间：
1994
影响因子：
2.7
通讯作者：
Lehrer,SS
中科院分区：
文献类型：
--
作者：
Lehrer,SS
Ca 2+和肌球蛋白头都参与调节，其中Ca 2+作为变构触发器，肌球蛋白头诱导的Tm关-开转换作为开关。变构/合作模型是一个很好的现象学描述的一部分的过程和方面的原始空间阻断模型涉及的分子机制。
Ca2+ and myosin heads are both involved in regulation, with Ca2+ as the allosteric trigger and the myosin head-induced Tm off-on transition as the switch. The allosteric/cooperative model is a good phenomenological description of part of the process and aspects of the original steric blocking model are involved in the molecular mechanisms.