Synthesis of novel palladacycles and their application in Heck and Suzuki reactions under aerobic conditions.
Synthesis of novel palladacycles and their application in Heck and Suzuki reactions under aerobic conditions.
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DOI：
10.1021/ol048749s
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发表时间：
2004-08
期刊：
影响因子：
5.2
通讯作者：
Zhengchang Xiong;Nengdong Wang;M. Dai;Ang Li;Jia-Hua Chen;Zhen Yang
中科院分区：
文献类型：
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作者：
Zhengchang Xiong;Nengdong Wang;M. Dai;Ang Li;Jia-Hua Chen;Zhen Yang
[反应：见正文]本文报道了一类新的呋喃硫代甲酰胺基钯杂环化合物的设计和合成。这些钯杂环是热稳定的，对空气或湿气不敏感，并且有效地应用于芳基卤化物与末端烯烃的Heck反应和芳基卤化物与芳基硼酸的Suzuki反应。这些反应在有氧条件下进行，导致周转数（TON）高达1 × 10（5）。
[reaction: see text] Design and synthesis of a novel family of furancarbothioamide-based palladacycles are reported herein. These palladacycles are thermally stable, not sensitive to air or moisture, and are applied effectively in the Heck reaction of aryl halides with terminal olefins and in the Suzuki reaction of aryl halides with arylboronic acids. These reactions were performed under aerobic conditions, leading to turnover numbers (TONs) up to 1 x 10(5).