Natural History of Wolff-Parkinson-White Syndrome Diagnosed in Childhood
Natural History of Wolff-Parkinson-White Syndrome Diagnosed in Childhood
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DOI：
10.1016/j.amjcard.2013.05.035
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发表时间：
2013-10-01
影响因子：
2.8
通讯作者：
Arora, Gaurav
中科院分区：
文献类型：
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作者：
Cain, Nicole;Irving, Claire;Arora, Gaurav
沃尔夫-帕金森-怀特（WPW）综合征具有症状性心律失常和猝死的风险。本研究的目的是检查儿童期诊断的沃尔夫-帕金森-怀特综合征患者的自然史，在单一机构进行纵向随访。研究人群包括446名患者。中位诊断年龄为7岁，61%为男性。40例患者（9%）存在相关心脏病。表现方式包括室上性心动过速（38%）、心悸（22%）、胸痛（5%）、晕厥（4%）、心房颤动（0.4%）、猝死（0.2%）和意外发现（26%）；4%的国家无法获得数据。在研究期间，共有243例（54%）患者发生室上性心动过速，7例（1.6%）患者发生房颤。在3个月大的患者中(p
Wolff-Parkinson-White (WPW) syndrome carries a risk for symptomatic arrhythmias and sudden death. The aim of this study was to examine the natural history of patients with Wolff-Parkinson-White syndrome diagnosed in childhood followed longitudinally at a single institution. The study population consisted of 446 patients. The median age of diagnosis was 7 years, and 61% were male. Associated heart disease was present in 40 patients (9%). Modes of presentation included supraventricular tachycardia (38%), palpitations (22%), chest pain (5%), syncope (4%), atrial fibrillation (0.4%), sudden death (0.2%), and incidental findings (26%); data were unavailable in 4%. During the study period, a total of 243 patients (54%) had supraventricular tachycardia, and 7 patients (1.6%) had atrial fibrillation. Of patients who presented at 3 months of age (p