Detection of ovarian tumors in chicken by sonography - A step toward early diagnosis in humans?
Detection of ovarian tumors in chicken by sonography - A step toward early diagnosis in humans?
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DOI：
10.7863/jum.2007.26.7.909
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发表时间：
2007-07-01
影响因子：
2.3
通讯作者：
Luborsky, Judith L.
中科院分区：
文献类型：
--
作者：
Barua, Animesh;Abramowicz, Jacques S.;Luborsky, Judith L.
Objective.自发性卵巢癌的动物模型对于了解肿瘤的早期发展是很重要的。卵巢显像在跟踪肿瘤发展变化中可能发挥重要作用。蛋鸡是唯一一种与人类相似的自发性卵巢癌动物。本研究的目的是确定的可行性检测卵巢肿瘤在蛋鸡超声。方法.应用经阴道二维灰阶和彩色多普勒超声对29只2.5-3.0岁的白色来航蛋鸡卵巢进行了检查。超声评价与卵巢解剖和组织学特征进行了比较。结果体内超声检查结果与卵巢解剖学和组织学检查结果一致。通过超声检查，在所有母鸡中均正确检测到卵巢肿瘤。卵巢肿瘤患者的阻力指数和搏动指数均低于正常卵巢（P
Objective. Animal models of spontaneous ovarian cancer are important for understanding early tumor development. Ovarian imaging may play an important role in following changes in tumor development. Laying hens are the only animals that develop spontaneous ovarian cancer similar to humans. The aim of this study was to determine the feasibility of detecting ovarian tumors in laying hens using sonography. Methods. Ovaries of commercial strains of White Leghorn laying hens (n = 29, 2.5-3.0 years old) were examined by transvaginal 2-dimensional gray scale and color Doppler sonography. Sonographic evaluations were compared with ovarian anatomy and histologic features. Results. Results of in vivo sonography and ovarian anatomic and histologic examinations were consistent. The presence of gross ovarian tumors was correctly detected in all hens by sonography. The resistive and pulsatility index values associated with ovarian tumors were lower than for normal ovaries (P