Gold nanoparticles induce oxidative damage in lung fibroblasts in vitro
Gold nanoparticles induce oxidative damage in lung fibroblasts in vitro
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DOI：
10.1002/adma.200701853
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发表时间：
2008-01-07
影响因子：
29.4
通讯作者：
Yung, Lin-Yue Lanry
中科院分区：
文献类型：
--
作者：
Li, Jasmine J.;Zou, Li;Yung, Lin-Yue Lanry
评估与使用纳米颗粒相关的健康风险是一个重要的研究领域。在这里，金纳米粒子（AuNPs）对人胚肺成纤维细胞的影响进行了研究。该图显示肺成纤维细胞对AuNP的摄取。大多数纳米颗粒被内吞并存在于核（N）周围的囊泡（箭头）中。然而，在胞质溶胶中发现了一些颗粒（红圈）。
Evaluation of the health risks associated with the use of nanometer-sized particles constitutes an important research field. Here, the effect of gold nanoparticles (AuNPs) on human embryonic lung fibroblasts is investigated. The figure shows the uptake of AuNPs by lung fibroblasts. Most nanoparticles are endocytosed and found in vesicles (arrows) around the nucleus (N). However, some particles are found in cytosol (red circle).