Oligosaccharide portion of GM1 enhances process formation by S20Y neuroblastoma cells.
Oligosaccharide portion of GM1 enhances process formation by S20Y neuroblastoma cells.
复制标题
GM1 的寡糖部分增强 S20Y 神经母细胞瘤细胞的过程形成。
DOI：
10.1111/j.1471-4159.1988.tb04867.x
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发表时间：
1988
影响因子：
4.7
通讯作者：
Prouty,C
中科院分区：
文献类型：
--
作者：
Schengrund,CL;Prouty,C
The oligosaccharide portion of ganglioside GM1 was found to enhance neuritogenesis by S20Y murine neuroblastoma cells grown in vitro. The average length of the neurites produced by cells grown in the presence of the oligosaccharide portion of GM1 was comparable to that of cells grown in the presence of intact GM1. The processes of these cells were significantly longer (p < 0.005, pooledttest) than those of cells grown in the presence of comparable concentrations of sialic acid, lactose, sialyllactose, GD1a, or the oligosaccharide moiety of GD1a. These results suggest that it is the oligosaccharide portion of GM1 that is responsible for the ability of GM1 to enhance process outgrowth by S20Y neuroblastoma cells.
