Photorepair of ultraviolet radiation (UVR)-induced pyrimidine dimers in lens epithelial DNA of Monodelphis domestica.
Photorepair of ultraviolet radiation (UVR)-induced pyrimidine dimers in lens epithelial DNA of Monodelphis domestica.
复制标题
紫外线辐射 (UVR) 诱导的 Monodelphis Domestica 晶状体上皮 DNA 中嘧啶二聚体的光修复。
DOI:
10.1111/j.1751-1097.1997.tb01887.x
复制
发表时间:
1997
影响因子:
3.3
通讯作者:
Ley,RD
中科院分区:
文献类型:
--
作者:
Tafoya,GB;Gale,JM;Ley,RD
The repair of UV radiation‐induced pyrimidine dimers has been measured in lens epithelial DNA of the marsupialMonodelphis domesticausing a pyrimidine dimerspecific endonuclease fromMicrococcus luteus.Approximately 40% of the initially induced dimers were repaired during 90 min exposures to photoreactivating light. This capacity of the lens epithelium to photorepair pyrimidine dimers may provide a means with which to determine whether pyrimidine dimers in lens epithelial DNA are involved in UV radiation‐induced pathologic changes of the lens.