Influences of age, viral load, and CD4+ count on the rate of progression of HIV-1 infection to AIDS. Transfusion Safety Study Group.

Influences of age, viral load, and CD4+ count on the rate of progression of HIV-1 infection to AIDS. Transfusion Safety Study Group.
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年龄、病毒载量和 CD4 计数对 HIV-1 感染进展为 AIDS 的速度有影响。

DOI:
10.1097/00042560-199707010-00009
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发表时间:
1997
期刊:
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association
影响因子:
--
通讯作者:
Stram,DO
Stram,DO
中科院分区:
--
文献类型:
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作者:
Operskalski,EA;Mosley,JW;Busch,MP;Stram,DO

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年轻人似乎能够对HIV-1感染产生更有效的免疫反应,表现为病毒载量较低,CD 4+细胞水平较高,进展为临床艾滋病的速度较慢。年龄对HIV-1进展的影响是复杂的,必须用高病毒载量以外的因素来解释。
It appears that younger persons may be able to mount a more effective immunological response to HIV-1 infection, which is manifested by lower levels of viral load, higher levels of CD4+cells, and less rapid progression to clinical AIDS. The effect of age on HIV-1 progression is complex and must be explained by factors other than a high viral load.