Nasal inoculation of an adenovirus vector encoding 11 tandem repeats of Abeta1-6 upregulates IL-10 expression and reduces amyoid load in a Mo/Hu APPswe PS1dE9 mouse model of Alzheimer's disease.
Nasal inoculation of an adenovirus vector encoding 11 tandem repeats of Abeta1-6 upregulates IL-10 expression and reduces amyoid load in a Mo/Hu APPswe PS1dE9 mouse model of Alzheimer's disease.
复制标题
在阿尔茨海默病的 Mo/Hu APPswe PS1dE9 小鼠模型中,经鼻接种编码 11 个串联重复 Abeta1-6 的腺病毒载体可上调 IL-10 表达并减少淀粉样蛋白负荷。
DOI:
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发表时间:
2007
期刊:
影响因子:
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通讯作者:
Fukuchi K.
中科院分区:
文献类型:
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作者:
Kim HD;Tahara K;Maxwell JA;Lalonde R;Fukuiwa T;Fujihashi K;Van Kampen KR;Kong FK;Tang DC;Fukuchi K.