Controlled biosilification using self-assembled short peptides A6K and V6K
Controlled biosilification using self-assembled short peptides A6K and V6K
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DOI：
10.1039/c2ra22099g
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发表时间：
2013-01-01
期刊：
影响因子：
3.9
通讯作者：
Lin, Yuejuan
中科院分区：
文献类型：
--
作者：
Wang, Qinrong;Yu, Jun;Lin, Yuejuan
我们报告了两种两亲性肽（A(6)K 和 V6K）的分子自组装，以及它们的自组装作为有机模板的应用，以指导生物二氧化硅的形成。在环境条件下，A(6)K 自组装成 2.7 nm 高、约 1 μm 至 2 μm 长的纳米管。相比之下，V6K 自组装成层状堆叠纳米结构，高约 4 nm，长约 100 nm。自组装肽纳米结构被用作有机模板来指导生物二氧化硅的形成。与肽/阴离子系统形成的自组装结构相比，通过改变肽组成、使用不同的阴离子以及施加静电/流场可以获得新的二氧化硅形态。我们观察到阴离子的存在很重要，但不足以产生具有新颖形态的有序二氧化硅结构。这项研究进一步了解了通过组装肽定制的二氧化硅生物矿化，这提供了一种简单但有效的方法来控制无机材料的形成。
We report the molecular self-assembly of two amphiphilic peptides (A(6)K and V6K) and the application of their self-assemblies as organic templates to direct biosilica formation. Under ambient conditions, A(6)K self-assembled into nanotubes 2.7 nm tall and approximately 1 mu m to 2 mu m long. In contrast, V6K self-assembled into lamellar-stack nanostructures approximately 4 nm tall and under 100 nm long. The self-assembled peptide nanostructures were used as organic templates to direct biosilica formation. Comparing with the self-assembled structures formed by the peptide/anions system, novel silica morphologies can be obtained by changing the peptide composition, using different anions, and applying electrostatic/flow fields. We observed that the presence of anions is important but not enough to produce ordered silica structures with novel morphologies. This study provides further understanding of silica biomineralization tailored by assembled peptides, which offers a simple but efficient method to control the formation of inorganic material.