Interhemispheric transcallosal connectivity between the left and right planum temporale predicts musicianship, performance in temporal speech processing, and functional specialization
Interhemispheric transcallosal connectivity between the left and right planum temporale predicts musicianship, performance in temporal speech processing, and functional specialization
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DOI：
10.1007/s00429-014-0910-x
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发表时间：
2016-01-01
影响因子：
3.1
通讯作者：
Jaencke, Lutz
中科院分区：
文献类型：
--
作者：
Elmer, Stefan;Haenggi, Juergen;Jaencke, Lutz
目前，有强有力的证据表明，音乐才能有利于左颞平面（PT）的功能和结构变化，并且这些皮质重组有助于辨别颞部言语线索。基于左右 PT 之间的分工命题，我们假设音乐家在处理时间言语线索和 PT 专业化方面的优势至少部分源于两个听觉相关皮层之间白质连接的增加。特别是，我们假设增加的胼胝体 PT 连接可能促进同位脑区域的功能专业化和不对称性。考虑到这一目的，我们应用扩散张量成像，并比较了 13 名音乐家和 13 名非音乐家的左右 PT 之间的半球间连接的轴向扩散率 (AD)、径向扩散率 (RD) 和分数各向异性 (FA)。此外，我们以附录的形式整合了左侧 PT 的皮质表面积值和血氧水平依赖性 (BOLD) 反应，这些值是在之前对同一受试者样本进行的两项研究中收集的。我们的结果表明，与非音乐家相比，音乐家左、右 PT 之间的连接性有所增加，如平均 RD 减少所示。我们没有发现 FA 和 AD 的组间显着差异。最值得注意的是，RD 与语音分类任务中的表现、音乐才能以及左侧 PT 中的大胆反应有关。因此，我们为 PT 连接、音乐才能和语音分类之间的关系提供了第一个证据。
Currently, there is strong evidence showing that musicianship favours functional and structural changes of the left planum temporale (PT), and that these cortical reorganizations facilitate the discrimination of temporal speech cues. Based on the proposition of a division of labour between the left and right PT, here we postulated that the musicians' advantage in processing temporal speech cues and PT specialization origin, at least in part, from increased white matter connectivity between the two auditory-related cortices. In particular, we assume that increased transcallosal PT connectivity might promote functional specialization and asymmetry of homotopic brain regions. With this purpose in mind, we applied diffusion tensor imaging and compared axial diffusivity (AD), radial diffusivity (RD), and fractional anisotropy (FA) of the interhemispheric connection between the left and right PT in thirteen musicians and 13 nonmusicians. Furthermore, in the form of an addendum, we integrated cortical surface area values and blood oxygenation level dependent (BOLD) responses of the left PT that were collected in the context of two previous studies conducted with the same sample of subjects. Our results indicate increased connectivity between the left and right PT in musicians compared to nonmusicians, as indexed by reduced mean RD. We did not find significant between-group differences in FA and AD. Most notably, RD was related to the performance in the phonetic categorization task, musical aptitudes, as well as to BOLD responses in the left PT. Hence, we provide first evidence for a relationship between PT connectivity, musicianship, and phonetic categorization.