Refractive error and glaucoma
Refractive error and glaucoma
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DOI：
10.1034/j.1600-0420.2001.790603.x
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发表时间：
2001-12-01
期刊：
影响因子：
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通讯作者：
Bengtsson, B
中科院分区：
文献类型：
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作者：
Grodum, K;Heijl, A;Bengtsson, B
目的：研究屈光不正、青光眼损害与眼压之间的关系。方法：我们调查了瑞典马尔莫市32918名57-79岁的居民，寻找未发现青光眼的个体。用自动验光仪测量屈光度。用Humphrey Full Threshold 24-2程序将青光眼损害定义为可复制的视野缺陷。结果：青光眼患病率与屈光状态明显相关，随着近视程度的增加，青光眼患病率逐渐增加。这在男性和女性中都可以看到，并在整个年龄范围内持续存在。青光眼在近视眼中比在低眼压读数的远视眼中更常见(p=0.024)。近视眼青光眼的过度表现随着眼压的升高而下降，而在眼压大于或等于31 mm Hg的眼中，青光眼的过度表现没有相关性。结论：在这个庞大的人群中，青光眼的患病率随着近视的增加而增加。近视和青光眼之间的相关性在较低的眼压水平时很强，随着眼压的升高而逐渐减弱。我们的研究结果表明，近视是青光眼，特别是正常眼压性青光眼的重要危险因素。
Purpose: To study the association between refractive error, glaucoma damage and IOP in a large population.Methods: We examined 32,918 citizens of the city of Malmo, Sweden, 57-79 years of age, searching for individuals with undetected glaucoma. Refraction was measured with autorefractors. Glaucoma damage was defined as reproducible visual field defects with the Humphrey Full Threshold 24-2 program.Results: Glaucoma prevalence was clearly associated with refractive state, increasing gradually with increasing myopia. This was seen both in males and females and persisted over the full age range. Glaucoma was significantly more common in myopic than in hyperopic eyes with low IOP readings (p=0.024). The overrepresentation of glaucoma in myopic eyes declined with increasing IOP and no relationship was observed in eyes with IOP greater than or equal to 31 mmHg.Conclusion: In this large population, the prevalence of glaucoma increased with increasing myopia. The association between myopia and glaucoma was strong at lower IOP levels, and weakened gradually with increasing IOP. Our findings indicate that myopia is an important risk factor for glaucoma and particularly for normal tension glaucoma.