The effect of obesity on quality of life in patients with diabetes and coronary artery disease
The effect of obesity on quality of life in patients with diabetes and coronary artery disease
复制标题
DOI：
10.1016/j.ahj.2009.11.004
复制
发表时间：
2010-02-01
影响因子：
4.8
通讯作者：
Brooks, Maria M.
中科院分区：
文献类型：
--
作者：
Hlatky, Mark A.;Chung, Sheng-Chia;Brooks, Maria M.
肥胖增加了2型糖尿病和冠状动脉疾病（CAD）的风险。由于所有3个条件可能会降低生活质量，在何种程度上肥胖，糖尿病和CAD独立影响生活质量是undetermined.Methods患者2型糖尿病和记录CAD参与旁路血管成形术血运重建调查2糖尿病试验在45个临床站点在美国和加拿大进行了研究，在一个横断面分析的基线数据。生活质量进行了评估与杜克活动状态指数，能源/疲劳和健康困扰量表的医疗结果Study. Results，整体自测健康状况。结果较高的体重指数与所有4个生活质量量表评分较差，即使调整后的糖尿病和CAD和其他共病的严重程度。使用胰岛素，心绞痛，目前吸烟也与所有4个量表的生活质量显着降低，独立于其他factor.Conclusions肥胖与糖尿病和CAD患者的生活质量显着降低，独立于共病条件。(Am Heart J 2010; 159：292-300.）
Background Obesity increases the risk of type 2 diabetes and coronary artery disease (CAD). Because all 3 conditions may reduce quality of life, the extent to which obesity, diabetes, and CAD independently affect quality of life is uncertain.Methods Patients with type 2 diabetes and documented CAD participating in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial at 45 clinical sites in the United States and Canada were studied in a cross-sectional analysis of baseline data. Quality of life was assessed with the Duke Activity Status Index, the energy/fatigue and health distress scales from the Medical Outcome Study, and overall self-rated health status.Results Higher body mass index was significantly associated with worse scores on all 4 quality of life scales, even after adjustment for the severity of diabetes and CAD and other comorbid conditions. Use of insulin, angina, and current smoking were also associated with significantly lower quality of life on all 4 scales, independent of other factors.Conclusions Obesity is associated with significantly reduced quality of life in patients with diabetes and CAD, independent of comorbid conditions. (Am Heart J 2010; 159:292-300.)