Neonatal seizures: an update on mechanisms and management.

Neonatal seizures: an update on mechanisms and management.
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DOI:
10.1016/j.clp.2009.08.001
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发表时间:
2009-12
影响因子:
2.1
通讯作者:
Jensen FE
Jensen FE
中科院分区:
医学4区
文献类型:
--
作者:
Jensen FE

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The lifespan risk of seizures is highest in the neonatal period. Currently used therapies have limited efficacy. Although the treatment of neonatal seizures has not significantly changed in the last several decades, there has been substantial progress in understanding developmental mechanisms that influence seizure generation and responsiveness to anticonvulsants. Here we provide an overview of current approaches to the diagnosis and treatment of neonatal seizures, identifying some of the recent insights about the pathophysiology of neonatal seizures that may provide the foundation for better treatment.
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