SECONDARY METABOLITES OF THE ASPEN FUNGUS STACHYBOTRYS-CYLINDROSPORA
SECONDARY METABOLITES OF THE ASPEN FUNGUS STACHYBOTRYS-CYLINDROSPORA
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DOI：
10.1139/v93-069
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发表时间：
1993-04-01
期刊：
影响因子：
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通讯作者：
MIAO, S
中科院分区：
文献类型：
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作者：
AYER, WA;MIAO, S
对已知对青霉菌Ceratcystiopsis crassivan inata有较强拮抗作用的柱状孢子菌产生的次生代谢产物进行了检测。负责抗真菌活性的化合物是毛霉素(5)和毛霉酚(6)，这是两种已知的真菌毒素，属于毛霉烯家族。其他代谢产物水苏糖苷(1)、水苏胺(8)和6，8-二羟基-3，5，7-三甲基异色满(7)虽然对粗壮线虫没有活性，但都是新的天然产物。通过波谱技术确定了新化合物的结构。
The secondary metabolites produced by the fungus Stachybotrys cylindrospora, which is known to be strongly antagonistic to the blue-stain fungus Ceratocystiopsis crassivaginata, have been examined. The compounds responsible for the antifungal activity are trichodermin (5) and trichodermol (6), two previously known mycotoxins belonging to the trichothecene family. The other metabolites, stachybotrydial (1), stachybotramide (8), and 6,8-dihydroxy-3,5,7-trimethylisochroman (7), although not active against C. crassivaginata, are new natural products. The structures of the new compounds were established by spectroscopic techniques.