In Vitro Expansion of Stem Cells

In Vitro Expansion of Stem Cells
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干细胞的体外扩增

DOI:
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发表时间:
1999
期刊:
影响因子:
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通讯作者:
G. Zant
G. Zant
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作者:
G. Zant

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体外细胞生物反应器系统忠实地重建正常造血的许多生理方面,包括干细胞复制,可以在移植医学中起到几个重要的作用。这些包括(a)选择性地产生用于输注的细胞以满足移植环境中的特定需要;(B)选择性地从移植物中清除肿瘤细胞;以及(c)创造造血细胞可以被遗传工程化用于治疗用途的环境。
An in vitro cell bioreactor system faithfully re-creating many physiologic aspects of normal hematopoiesis, including stem cell replication, could serve several important purposes in transplantation medicine. These include (a) selectively producing cells for infusion to meet specific needs in the transplantation setting; (b) selectively purging tumor cells from grafts; and (c) creating an environment in which hematopoietic cells can be genetically engineered for therapeutic uses.
DOI: 10.1182/blood.v89.11.3991
发表时间: 1997-06
期刊: Blood
影响因子: 20.3
作者:
Felipe Prósper;Kirk Vanoverbeke;David F. Stroncek;Catherine M. Verfaillie
通讯作者: Felipe Prósper;Kirk Vanoverbeke;David F. Stroncek;Catherine M. Verfaillie