Development of a disease specific quality of life (QoL) questionnaire module to supplement the EORTC core cancer QoL questionnaire, the QLQ-C30 in patients with pancreatic cancer
Development of a disease specific quality of life (QoL) questionnaire module to supplement the EORTC core cancer QoL questionnaire, the QLQ-C30 in patients with pancreatic cancer
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DOI：
10.1016/s0959-8049(99)00047-7
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发表时间：
1999-06-01
影响因子：
8.4
通讯作者：
Tihanyi, T
中科院分区：
文献类型：
--
作者：
Fitzsimmons, D;Johnson, CD;Tihanyi, T
有压倒性的共识，生活质量评估是迫切需要在胰腺癌，但很少有研究已经进行。我们使用EORTC生活质量研究组的模块开发指南，报告了疾病特异性问卷模块的开发，以补充EORTC核心癌症模块，胰腺癌患者的QLQ-C30。通过文献检索和与卫生专业人员和胰腺癌患者的访谈，产生了相关的生活质量问题。问题被构建成项目并临时翻译。在8个欧洲中心的患者中对临时模块进行了预测试。由此产生的QLQ-PAN模块26包括与胰腺癌特有的疾病症状、治疗副作用和情绪问题相关的26个项目。这应确保该模块对评估胰腺癌中微小但重要的疾病和治疗相关QoL变化具有敏感性。QLQ-C30和QLQ-PAN 26的使用将在胰腺癌的国际试验中提供一个全面的QoL评估系统。(C)1999 Elsevier Science Ltd.保留所有权利。
There is overwhelming consensus that quality of Life assessment is urgently required in pancreatic cancer, yet little research has been conducted. We report on the development of a disease specific questionnaire module to supplement the EORTC core cancer module, the QLQ-C30 in patients with pancreatic cancer, using EORTC quality of life study group guidelines for module development. Relevant QoL issues were generated from literature searches and interviews with health professionals and patients with pancreatic cancer. Issues were constructed into items and provisionally translated. The provisional module was pretested in patients in 8 European centres. The resulting module the QLQ-PAN26 includes 26 items related to disease symptoms, treatment side-effects and emotional issues specific to pancreatic cancer. This should ensure that the module will be sensitive to assess the small but important disease and treatment related QoL changes in pancreatic cancer. The use of the QLQ-C30 and QLQ-PAN26 will provide a comprehensive system of QoL assessment in international trials of pancreatic cancer. (C) 1999 Elsevier Science Ltd. All rights reserved.