LIFETIME LEISURE EXERCISE AND OSTEOPOROSIS - THE RANCHO-BERNARDO STUDY
LIFETIME LEISURE EXERCISE AND OSTEOPOROSIS - THE RANCHO-BERNARDO STUDY
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DOI：
10.1093/oxfordjournals.aje.a117362
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发表时间：
1995-05-15
影响因子：
5
通讯作者：
HAILE, R
中科院分区：
文献类型：
--
作者：
GREENDALE, GA;BARRETTCONNOR, E;HAILE, R
在1988年至1991年期间，在一组平均年龄为73岁的社区居住的加州成年人（1,014名女性和689名男性）中，评价了休闲时间体力活动、骨矿物质密度（BMD）和骨质疏松性骨折之间的关系。通过修改后的Paffenbarger问卷，参与者被要求报告过去一年的运动情况，并回忆他们在其他三个时期的运动水平：青少年时期，30岁和50岁。调查询问了剧烈运动的次数（例如，慢跑），中等（例如，快速行走），或轻度（例如，高尔夫球）运动。构建了一个概括评分来代表终身锻炼。分别采用逻辑回归和线性回归分析对运动性骨折和运动性骨密度进行相关性分析。线性回归模型控制了年龄、体重指数、性别、关节炎诊断、膳食钙摄入量、吸烟、饮酒、噻嗪类药物和雌激素（仅限女性）。目前或以前的运动与桡骨、腕关节或脊柱的BMD之间没有相关性，而与全髋关节（p = 0.001）和每个髋关节部件-大转子（p = 0.02）、转子间（p = 0.001）和股骨颈（p = 0.02）的BMD之间存在正相关性。剧烈（p = 0.004）和中度（p = 0.004）当前锻炼者的平均髋骨密度高于轻度或低于轻度锻炼者。终身锻炼也与全髋关节（p = 0.008）和髋关节部件的BMD呈正相关，并与脊柱BMD呈边缘显著相关（p = 0.06）。在髋部，终身运动的最高和最低三分位数之间的每对比较都显示出显著差异（p小于或等于0.007）。运动与1972年至1991年间任何部位发生的轻微创伤骨折无关。这些数据表明，当前和终身锻炼对老年男性和女性的髋部BMD有保护作用，但对骨质疏松性骨折无保护作用。
Between 1988 and 1991,the relation between leisure time physical activity, bone mineral density (BMD), and osteoporotic fracture was evaluated in a cohort of community-dwelling California adults (1,014 women and 689 men) with a mean age of 73 years. By means of a modified Paffenbarger questionnaire, participants were asked to report exercise from the past year and to recall their level of exercise during three other periods: the teenage years, age 30 years, and age 50 years. The survey asked the number of times strenuous (e.g., jogging), moderate (e.g., fast walking), or mild (e.g., golfing) exercise was undertaken in an average week. A summary score was constructed to represent lifetime exercise. Analyses of the exercise-fracture and exercise-BMD associations were performed using logistic and linear regression analyses, respectively. Linear regression models were controlled for age, body mass index, sex, diagnosis of arthritis, dietary calcium intake, and use of cigarettes, alcohol, thiazides, and estrogen (women only). No association between current or former exercise and BMD at the radius, wrist, or spine was found. A positive association between current exercise and BMD was found at the total hip (p = 0.001) and at each hip component-greater trochanter (p = 0.02), intertrochanter (p = 0.001), and femoral neck (p = 0.02). Mean hip bone densities of strenuous (p = 0.004) and moderate (p = 0.004) current exercisers were higher than those of mild or less than mild exercisers. Lifetime exercise was also positively associated with BMD of the total hip (p = 0.008) and hip components, and demonstrated a borderline-significant association (p = 0.06) with spine BMD. At the hip, each pairwise comparison between the highest and lowest tertiles of lifetime exercise showed a significant difference (p less than or equal to 0.007). Exercise was unassociated with minimal trauma fracture occurring at any site between 1972 and 1991. These data suggest a protective effect of current and lifelong exercise on hip BMD, but not on osteoporotic fracture, in older men and women.