Effect of cooling area 18 on striate cortex cells in the squirrel monkey.
Effect of cooling area 18 on striate cortex cells in the squirrel monkey.
复制标题
冷却区域 18 对松鼠猴纹状皮层细胞的影响。
DOI：
10.1152/jn.1982.48.1.38
复制
发表时间：
1982
影响因子：
2.5
通讯作者：
Schiller,PH
中科院分区：
文献类型：
--
作者：
Sandell,JH;Schiller,PH
松鼠猴（Saimiri sciureus）的纹状皮质（17区）与相邻的纹外视觉区（18区）相连。Tigges等人(15)使用银变性技术证明了这一点，Tigges等人已经扩展和阐述了他们的工作。(17)和Wong-Riley（20）使用辣根过氧化物酶和氚化氨基酸标记的组合。纹状皮质从第II层和第III层发出一个投影，它主要终止于第IV层，即视网膜定位对应的区域18。区域18的该部分又将投影发送回区域17的相应区域，其主要终止于层I、V和VI，尽管除了111的下部和层IV之外，其他层也在一定程度上被标记。在猕猴（Macaca mulatta）（10）和猫头鹰猴（Aotus trivirgatus）（7）中也描述了类似的连接。因此，纹状皮质和18区之间的相互关系似乎是灵长类动物皮质解剖学的共同特征。虽然这些连接的解剖结构现在是众所周知的，但它们的功能意义仍然是一个问题。从猕猴的研究中可以清楚地看到，18区接收来自17区的关键输入（11）。当这个输入被冷却区17暂时去除时，区18中的细胞变得完全无响应。然而，在猕猴中，从18区回到纹状体皮质的投影的意义并不容易解决，因为18区的大部分无法冷却。因此，我们选择研究这种投射的功能意义
The striate cortex (area 17) of the squirrel monkey (Saimiri sciureus) is reciprocally connected to the adjacent extrastriate visual area (area 18). Tigges et al.(15) demonstrated this using silver-degeneration techniques and their work has been expanded and elaborated by Tigges et al.(17) and Wong-Riley (20) using a combination of horseradish peroxidase and tritiated amino acid labeling. Striate cortex sends a projection from layers II and III, which terminates largely in layer IV, of the retinotopically corresponding region of area 18. This part of area 18, in turn, sends a projection back to the corresponding region of area 17, which terminates predominately in layers I, V, and VI, although other layers are also labeled to some extent, except for the lower part of 111~ and layer IV. Connections similar to these have also been described in the macaque (Macaca mulatta)(10) and in the owl monkey (Aotus trivirgatus)(7). Thus, the reciprocal relationship between striate cortex and area 18 appears to be a common feature of the cortical anatomy of primates. While the anatomy of these connections is now well known, their functional significance remains a question. It is clear from work in the macaque that area 18 receives a crucial input from area 17 (11). When this input was temporarily removed by cooling area 17, cells in area 18 became completely unresponsive. The significance of the projection from area 18 back to striate cortex could not be easily addressed in the macaque, however, since most of area 18 is inaccessible to cooling. We chose therefore to investigate the functional significance of this projection