Pharyngeal Swallowing Mechanics Secondary to Hemispheric Stroke
Pharyngeal Swallowing Mechanics Secondary to Hemispheric Stroke
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DOI：
10.1016/j.jstrokecerebrovasdis.2016.11.001
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发表时间：
2017-05-01
影响因子：
2.5
通讯作者：
Pearson, William G., Jr.
中科院分区：
文献类型：
--
作者：
May, Nelson H.;Pisegna, Jessica M.;Pearson, William G., Jr.
背景：吞咽力学计算分析（CASM）是一种利用多变量形状变化分析来揭示与电视荧光吞咽研究损伤相关的咽部吞咽力学协变元素的方法。这项初步研究的目标是（1）表征中风相关吞咽困难的吞咽机制，（2）破译左右半球中风对咽部吞咽机制的影响，以及（3）确定与刺入-误吸状态相关的咽部吞咽机制。方法：从严格控制的数据集中选取 18 名患有半球梗塞的吞咽困难患者以及年龄和性别匹配的对照者进行电视透视吞咽研究。收集患者数据，包括偏侧性和穿刺抽吸状态。从视频中收集绘制吞咽过程中肌肉群动作的坐标。对与中风、受影响的半球和穿刺-抽吸状态相关的坐标进行了多变量形态测量分析。结果：咽部吞咽力学在以下比较中存在显着差异：中风与对照组（D = 2.19，P < .0001），右半球中风与对照组（D = 3.64，P
Background: Computational analysis of swallowing mechanics (CASM) is a method that utilizes multivariate shape change analysis to uncover covariant elements of pharyngeal swallowing mechanics associated with impairment using videofluoroscopic swallowing studies. The goals of this preliminary study were to (1) characterize swallowing mechanics underlying stroke-related dysphagia, (2) decipher the impact of left and right hemispheric strokes on pharyngeal swallowing mechanics, and (3) determine pharyngeal swallowing mechanics associated with penetration-aspiration status. Methods: Videofluoroscopic swallowing studies of 18 dysphagic patients with hemispheric infarcts and ageand gender-matched controls were selected from well-controlled data sets. Patient data including laterality and penetration-aspiration status were collected. Coordinates mapping muscle group action during swallowing were collected from videos. Multivariate morphometric analyses of coordinates associated with stroke, affected hemisphere, and penetration-aspiration status were performed. Results: Pharyngeal swallowing mechanics differed significantly in the following comparisons: stroke versus controls (D = 2.19, P < .0001), right hemispheric stroke versus controls (D = 3.64, P