Replication strategies of the single stranded RNA viruses of eukaryotes.
Replication strategies of the single stranded RNA viruses of eukaryotes.
复制标题
真核生物单链RNA病毒的复制策略。
DOI：
10.1007/978-3-642-69159-1_1
复制
发表时间：
1983
影响因子：
--
通讯作者：
Strauss,JH
中科院分区：
文献类型：
--
作者：
Strauss,EG;Strauss,JH
在过去的几年里，我们对病毒复制的分子生物学知识有了显著的扩展，特别是随着获得病毒基因组核苷酸序列的快速技术的出现。病毒基因组的全部或部分序列每月都会出现，现在似乎有必要回顾一下RNA动物病毒复制所使用的策略，以期建立一个概念框架来组织新的序列信息。本章将关注通过RNA中间体复制的单链RNA病毒，并将重点放在动物病毒上，但也将讨论复制策略已知的选定植物病毒。主要的主题将是RNA转录（病毒特异性信息的产生），RNA复制（病毒基因组的合成）和mRNA翻译（病毒蛋白质的合成和加工）。
Our knowledge of the molecular biology of virus replication has expanded dramatically in the last few years, especially with the advent of rapid techniques for obtaining the nucleotide sequence of viral genomes. Full or partial sequences of virus genomes are appearing monthly, and it seems appropriate at this time to review the subject of the strategies used for replication by RNA animal viruses in the hope of formulating a conceptual framework in which to organize the new sequence information. This chapter will be concerned with the single-stranded RNA viruses which replicate via RNA intermediates and will focus on the animal viruses, but selected plant viruses whose replication strategies are known will also be discussed. The primary topics will be RNA transcription (the production of virus-specific messages), RNA replication (synthesis of viral genomes), and mRNA translation (synthesis and processing of viral proteins).