Decision-Making in Individuals with Agenesis of the Corpus Callosum: Expectancy-Valence in the Iowa Gambling Task
Decision-Making in Individuals with Agenesis of the Corpus Callosum: Expectancy-Valence in the Iowa Gambling Task
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DOI：
10.1093/arclin/acs052
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发表时间：
2012-08-01
影响因子：
2.6
通讯作者：
Paul, Lynn K.
中科院分区：
文献类型：
--
作者：
Brown, Warren S.;Anderson, Luke B.;Paul, Lynn K.
胼胝体发育不全的个体可以具有正常范围内的智力，但在决策和解决复杂的新问题方面存在缺陷。这些问题的具体性质尚未得到明确理解。采用爱荷华州赌博任务测试40名完全或部分ACC（全面智商80）和26名对照者的决策能力和解决问题的能力。期望效价（EV）模型被应用到每个参与者的试验的试验响应，以阐明每组使用的决策过程中的差异。与对照组相比，ACC组的总体净收益较低，有利选择较少，但这些差异在统计学上并不显著。在EV模型中，ACC的个体对损失表现出更高的关注度，他们选择策略的一致性较低，并且在甲板之间切换的频率更高。他们还表现出更受最近试验影响的趋势。这一结果类似于在患有帕金森氏症的个体中所见。两者合计，这些结果表明，与ACC的个人有困难，在推断游戏突发事件，形成一个连贯的选择策略，涉及胼胝体在这些决策过程。
Individuals with agenesis of the corpus callosum (ACC) can have intelligence within the normal range, but nevertheless have deficiencies in decision-making and complex novel problem-solving. The specific nature of these problems is not yet clearly understood. The Iowa Gambling Task was used to test decision-making ability and problem-solving in 40 individuals with complete or partial ACC (full-scale intelligence quotient 80) and 26 control participants. The expectancy-valence (EV) model was applied to the trial-by-trial responses of each participant to elucidate differences in decision processes utilized by each group. The ACC group had a lower overall net gain and fewer advantageous choices than controls, but these differences were not statistically significant. Within the EV model, individuals with ACC exhibited significantly higher attention to losses, less consistency in their choice strategy, and greater frequency of switching between decks. They also showed a tendency to be more influenced by recent trials. This outcome is similar to that seen in individuals with Aspergers disorder. Taken together, these results suggest that individuals with ACC have difficulty in inferring game contingencies and forming a coherent selection strategy, implicating the corpus callosum in these decision processes.