A new subgroup of the family 2 cystatins
A new subgroup of the family 2 cystatins
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DOI：
10.1016/s0303-7207(02)00408-2
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发表时间：
2003-02-28
影响因子：
4.1
通讯作者：
Hsia, N
中科院分区：
文献类型：
--
作者：
Cornwall, GA;Hsia, N
The cystatins are a superfamily of cysteine protease inhibitors. Several genes including Cres (cystatin-related epididymal spermatogenic), testatin, and cystatin T, have been identified that are related to the family 2 cystatins but lack critical consensus sites important for cysteine protease inhibition. In addition, these genes are primarily expressed in the reproductive tract suggesting they may have evolved to perform tissue-specific functions distinct from that of the typical cystatins. This review describes the CRES subgroup within the family 2 cystatins including potential new members and their putative functions in the reproductive tract. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
