Quality of life and mood in women with gynecologic cancer - A one year prospective study
Quality of life and mood in women with gynecologic cancer - A one year prospective study
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DOI：
10.1002/cncr.10155
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发表时间：
2002-01-01
期刊：
影响因子：
6.2
通讯作者：
Ritchie, J
中科院分区：
文献类型：
--
作者：
Lutgendorf, SK;Anderson, B;Ritchie, J
背景对妇科癌症患者治疗第一年的生活质量（QOL）和情绪进行了前瞻性研究。探讨应对方式与生活质量和情绪的关系。招募了98例早期或局部晚期妇科癌症患者。在首次临床访视和1年时评估情绪和生活质量，并在两个时间点从图表中提取医疗信息。尽管区域性晚期患者在基线时报告了身体、功能和总体健康状况的下降，但到一年时，所有患者均报告了生活质量和情绪的显著改善。早期和区域晚期患者在这些指标的改善方面没有差异。控制的医疗变量和年龄，患者应对使用更大的接受和积极的重构在他们的首次访问报告更好的一年生活质量;那些持续较高水平的这些自适应应对策略在一年报告更好的并发功能和情感健康。在一年内寻求更多的社会支持与更好的社会福利和医患关系有关。相反，在研究开始时脱离应对与一年后较差的医患关系相关;一年后继续脱离应对与较差的同时生活质量和更大的痛苦相关。在治疗后的第一年，早期和局部晚期妇科肿瘤患者的生活质量和情绪都有所改善。使用脱离应对的患者尤其有生活质量差和痛苦的风险。(C)2002年美国癌症协会。
BACKGROUND. Quality of life (QOL) and mood were prospectively investigated during the first year of treatment among women with gynecologic cancers. Relationships of coping styles to QOL and mood were examined.METHODS. Ninety-eight patients with early stage or regionally advanced gynecologic cancers were recruited. Mood and QOL were assessed at initial clinic visit and at one year, and medical information was abstracted from charts at both timepoints.RESULTS. Although decrements in physical, functional, and total well-being were reported at baseline by regionally advanced patients, by one year, all patients reported significant improvements in QOL and mood. There were no differences between early stage and regionally advanced patients in their improvement for these measures. Controlling for medical variables and age, patients who coped using greater acceptance and positive reframing at their initial visits reported better one year QOL; those with continued higher levels of these adaptive coping strategies at one year reported better concurrent functional and emotional wellbeing. Greater seeking of social support at one year was associated with better concurrent social well-being and doctor-patient relationships. In contrast, disengaged coping at study entry was associated with poorer doctor-patient relationships at one year; continued disengagement at one year was associated with poorer concurrent QOL and greater distress.CONCLUSIONS. During the first year following treatment, QOL and mood improved among both early stage and regionally advanced gynecologic oncology patients. Patients using disengaged coping are particularly at risk for poor QOL and distress. (C) 2002 American Cancer Society.