ANALYSIS OF ELECTROLYTE MOVEMENT IN THIN HENLE'S LOOPS OF HAMSTER PAPILLA.
ANALYSIS OF ELECTROLYTE MOVEMENT IN THIN HENLE'S LOOPS OF HAMSTER PAPILLA.
复制标题
仓鼠乳头细亨利氏环中电解质运动的分析。
DOI：
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发表时间：
1965
影响因子：
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通讯作者：
Sidney Solomon
中科院分区：
文献类型：
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作者：
Donald J. Marsh;Sidney Solomon
盐溶液之间的油滴之间的Henle 9 s环的细肢的管腔内隔离保持在恒定的体积，而棉子糖溶液经历了连续的体积随时间增加。平衡后，组成的NaCl灌注液相对于渗透压和Na和Cl浓度变得类似的直血管血浆。这些结果是相同的上升和下降的肢体，并建议，没有节段运输盐积极。降支和直血管在所有条件下均为等电位;抗利尿期间升支为9 mV阴性，集合管为17 mV阴性。通过渗透性利尿或生理盐水停流微灌注消除上行肢体负性。离子浓度的测量表明，上升的肢体电位的抗利尿剂不是一个扩散的潜力，它的消失在渗透性利尿不是由于出现的扩散潜力的counsign。我们认为，上升肢体电位是一个流动的潜力，但收集管电位反映了积极的离子运输。
Saline solutions isolated between oil droplets within the lumen of thin limbs of Henle9s loops remained at constant volume, while raffinose solutions underwent a continuous volume increase with time. After equilibrium, composition of the NaCl perfusates with respect to osmolality and Na and Cl concentrations became similar to that of vasa recta plasma. These results were identical for both ascending and descending limbs and suggest that neither segment transports salt actively. Descending limbs and vasa recta were isopotential under all conditions; the ascending limb during antidiuresis is 9 mv negative, the collecting ducts 17 mv negative. Ascending limb negativity was abolished by osmotic diuresis or stopped-flow microperfusion with saline. Measurement of ion concentrations showed that the ascending limb potential of antidiuresis is not a diffusion potential, and that its disappearance during osmotic diuresis is not due to the appearance of a diffusion potential of countersign. We suggest that the ascending limb potential is a streaming potential, but that the collecting duct potential reflects active ion transport.