Acupuncture for Chronic Low Back Pain A Multicenter, Randomized, Patient-Assessor Blind, Sham-Controlled Clinical Trial
Acupuncture for Chronic Low Back Pain A Multicenter, Randomized, Patient-Assessor Blind, Sham-Controlled Clinical Trial
复制标题
DOI：
10.1097/brs.0b013e318275e601
复制
发表时间：
2013-04-01
期刊：
影响因子：
3
通讯作者：
Song, Mi-Yeon
中科院分区：
文献类型：
--
作者：
Cho, Yu-Jeong;Song, Yun-Kyung;Song, Mi-Yeon
研究设计。多中心、随机、患者评估者盲法、假对照临床试验。目的。旨在研究个性化设置的针灸治疗对于减少慢性腰痛 (cLBP) 参与者的烦恼的功效。背景数据摘要。腰痛是工作年龄成年人残疾的主要原因之一。针灸被认为是治疗 cLBP 的有效方法，但目前尚不清楚针灸是否优于安慰剂。 方法 来自 3 家韩国医疗医院的 130 名年龄在 18 至 65 岁之间且在试验前至少持续 3 个月患有非特异性腰痛的成年人参加了这项研究。参与者接受韩医医生为期6周以上（每周两次）的个性化真实针灸治疗或假针灸治疗。主要结果是视觉模拟量表 (VAS) 评分因 cLBP 烦扰程度的变化。次要结局包括疼痛强度的 VAS 评分和包括 Oswestry 残疾指数、一般健康状况（简表-36）和贝克抑郁量表 (BDI) 的问卷。结果 除 Oswestry 残疾指数外，两组之间没有观察到基线差异。 116 名参与者完成了治疗以及 3 个月和 6 个月的随访，其中 14 名受试者退出。在主要终点（8周），两组之间的烦扰VAS评分和cLBP疼痛强度评分存在显着差异（P < 0.05）。此外，这 2 个评分持续改善直至 3 个月随访（分别为 P = 0.011、P = 0.005）。两组的 Oswestry 残疾指数、Beck 抑郁量表和 Short Form-36 评分均有所改善，无组间差异。结论。这项随机假手术对照试验表明，对于 cLBP 参与者，针灸治疗在减少烦扰和疼痛强度方面比假手术对照显示出更好的效果。
Study Design. Multicenter, randomized, patient-assessor blind, sham-controlled clinical trial.Objective. To investigate the efficacy of acupuncture treatment with individualized setting for reduction of bothersomeness in participants with chronic low back pain (cLBP).Summary of Background Data. Low back pain is one of the main reasons of disability among adults of working age. Acupuncture is known as an effective treatment of cLBP, but it remains unclear whether acupuncture is superior to placebo.Methods One hundred thirty adults aged 18 to 65 years with nonspecific LBP lasting for at least last 3 months prior to the trial participated in the study from 3 Korean medical hospitals. Participants received individualized real acupuncture treatments or sham acupuncture treatments for more than 6 weeks (twice a week) from Korean Medicine doctors. Primary outcome was change of visual analogue scale (VAS) score for bothersomeness of cLBP. Secondary outcomes included VAS score for pain intensity and questionnaires including Oswestry Disability Index, general health status (Short Form-36), and Beck Depression Inventory (BDI).Results There were no baseline differences observed between the 2 groups, except in the Oswestry Disability Index. One hundred sixteen participants finished the treatments and 3- and 6-month follow-ups, with 14 subjects dropping out. Significant difference in VAS score for bothersomeness and pain intensity score of cLBP has been found between the 2 groups (P < 0.05) at the primary end point (8 wk). In addition, those 2 scores improved continuously until 3-month follow-up (P = 0.011, P = 0.005, respectively). Oswestry Disability Index, the Beck Depression Inventory, and Short Form-36 scores were also improved in both groups without group difference.Conclusion. This randomized sham-controlled trial suggests that acupuncture treatment shows better effect on the reduction of the bothersomeness and pain intensity than sham control in participants with cLBP.