A nested case-control study of sexual practices and risk factors for prevalent HIV-1 infection among young men in Kisumu, Kenya

A nested case-control study of sexual practices and risk factors for prevalent HIV-1 infection among young men in Kisumu, Kenya
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DOI:
10.1097/01.olq.0000261335.42480.89
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发表时间:
2007-10-01
影响因子:
3.1
通讯作者:
Moses, Stephen
Moses, Stephen
中科院分区:
医学4区
文献类型:
--
作者:
Mattson, Christine L.;Bailey, Robert C.;Moses, Stephen

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目的:调查肯尼亚基苏穆市年轻男性艾滋病流行的性行为和危险因素。目的:本研究的目的是确定基苏穆市与艾滋病相关的行为,以最大限度地提高未来预防计划的有效性。研究设计:在一项随机对照试验的背景下,从1337名未行包皮环切术的参与者中收集了终生性史,艾滋病毒感染率。65名男子(5%)艾滋病毒检测呈阳性。多元逻辑回归揭示了以下艾滋病毒的独立预测因素:年龄较大,教育程度较低,已婚,是天主教徒,> 4个终生性伴侣,先前治疗过STI,伴侣月经期间的性行为,曾经进行放血,以及在过去6个月内接受过医疗注射。之前的艾滋病毒检测和性交后清洗protection.Conclusions:这项分析证实了建立艾滋病毒的危险因素的重要性,并确定的做法,值得进一步调查。
Objectives: To investigate sexual practices and risk factors for prevalent HIV infection among young men in Kisumu, Kenya.Goal: The goal of this study was to identify behaviors associated with HIV in Kisumu to maximize the effectiveness of future prevention programs.Study Design: Lifetime sexual histories were collected from a nested sample of 1337 uncircumcised participants within the context of a randomized controlled trial of male circumcision to reduce HIV incidence.Results: Sixty-five men (5%) tested positive for HIV. Multiple logistic regression revealed the following independent predictors of HIV: older age, less education, being married, being Catholic, > 4 lifetime sex partners, prior treatment for an STI, sex during partner's menstruation, ever practicing bloodletting, and receipt of a medical injection in the last 6 months. Prior HIV testing and postcoital cleansing were protective.Conclusions: This analysis confirms the importance of established risk factors for HIV and identifies practices that warrant further investigation.