Genome differences among varicella-zoster virus isolates.
Genome differences among varicella-zoster virus isolates.
复制标题
水痘带状疱疹病毒分离株之间的基因组差异。
DOI：
10.1099/0022-1317-64-5-1031
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
J. Owens
中科院分区：
文献类型：
--
作者：
S. Straus;J. Hay;H. Smith;J. Owens
The DNAs of 17 isolates of varicella-zoster virus (VZV) were analysed by restriction endonuclease cleavage and agarose gel electrophoresis. By comparing gel patterns of DNAs cleaved with only a few enzymes, all epidemiologically distinct isolates were shown to be unique. Two isolates recovered from members of a family infected in a common-source outbreak were identical to each other (4/4 enzymes) but distinct from the other strains. In addition, three isolates recovered at different times during the course of a single episode of zoster in another individual were identical by endonuclease analysis (4/4 enzymes) but once again were distinct from all other isolates. The differences that have been recognized in cleavage profiles of all VZV strains reported thus far map into four regions of the viral genome. Two of these variable regions lie within the long unique sequences while the other differences appear to map in each of the inverted repeat sequences.
水痘带状疱疹病毒 DNA 以两种异构体存在。
DOI：
10.1073/pnas.79.1.156
发表时间：
1982
影响因子：
11.1
作者：
Ecker,JR;Hyman,RW
通讯作者：
Hyman,RW