Donor Complications Associated With Living Donor Liver Transplantation in Japan
Donor Complications Associated With Living Donor Liver Transplantation in Japan
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DOI：
10.1097/tp.0b013e3181aaccb0
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发表时间：
2009-07-15
期刊：
影响因子：
6.2
通讯作者：
Kiyosawa, Kendo
中科院分区：
文献类型：
--
作者：
Hashikura, Yasuhiko;Ichida, Takafumi;Kiyosawa, Kendo
背景日本肝移植学会于2003年提交了第一份关于供体发病率的报告。该协会一直在继续调查在日本的活体肝脏捐赠者的结果。通过使用统一的综合病历审查程序，收集了截至2006年12月底日本38家中心3565例活体肝供体的数据。2例供体报告了术前问题，27例报告了术中问题，270例报告了术后并发症。总共有299名供体（8.4%）出现了与肝脏捐献相关的并发症。术后并发症包括3.0%的胆道并发症，1.3%的再次手术，2例（0.06%）的严重后遗症，1例供体（0.03%）的死亡（显然与供体手术相关）。左、右叶供者术后并发症发生率分别为8.7%和9.4%。累积的经验表明供体并发症的发生率降低，特别是右叶切除术。在日本18年的活体肝移植经验中，报告了一例供体死亡和两例与肝脏捐献相关的严重后遗症。
Background. The Japanese Liver Transplantation Society presented its first report on donor morbidity in 2003. The Society has been continuing to survey outcomes in living liver donors in Japan.Methods. By using a uniform comprehensive medical record review process, data were collected on 3565 living liver donors who had donated grafts by the end of December 2006 at 38 Japanese centers.Results. Preoperative problems were reported in 2 donors, intraoperative problems in 27, and postoperative complications in 270. In total, 299 donors (8.4%) suffered complications related to liver donation. Postoperative complications included biliary complications in 3.0%, reoperation in 1.3%, severe after-effects in two (0.06%), and death (apparently related to donor surgery) in one donor (0.03%). The incidence of postoperative complications in left and right lobe donors was 8.7% and 9.4%, respectively.Conclusions. The accumulated experience indicates a reduction in the incidence of donor complications, especially for right lobe resection. One donor death and two cases of severe after effects related to liver donation have been reported during 18 years of living donor liver transplantation experience in Japan.