Microbiome Modelling Toolbox 2.0: efficient, tractable modelling of microbiome communities.
Microbiome Modelling Toolbox 2.0: efficient, tractable modelling of microbiome communities.
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DOI:
10.1093/bioinformatics/btac082
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发表时间:
2022-04-12
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Constraint-Based Reconstruction and Analysis (COBRA) is a widely used approach for the interrogation and stratification of microbiome samples, yet applications to large-scale cohorts are hampered by limited scalability and efficiency of simulations. We substantially improved the computation speed and scalability of a previous implementation for the construction and interrogation of personalized constraint-based microbiome models as well as implemented additional functionalities for analysis and visualization. Microbiome Modelling Toolbox and tutorials are freely available as part of the COBRA Toolbox at https://git.io/microbiomeModelingToolbox.
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影响因子:
46.9
作者:
Magnusdottir, Stefania;Heinken, Almut;Thiele, Ines
通讯作者:
Thiele, Ines
影响因子:
12.2
作者:
Hertel J;Heinken A;Martinelli F;Thiele I
通讯作者:
Thiele I
影响因子:
14.8
作者:
Heirendt, Laurent;Arreckx, Sylvain;Fleming, Ronan M. T.
通讯作者:
Fleming, Ronan M. T.
影响因子:
5.8
作者:
Baldini, Federico;Heinken, Almut;Thiele, Ines
通讯作者:
Thiele, Ines
影响因子:
3
作者:
Gudmundsson S;Thiele I
通讯作者:
Thiele I