PROTONATION SITE OF VITAMIN-B1 AS DETERMINED FROM NATURAL-ABUNDANCE N-15 NUCLEAR MAGNETIC-RESONANCE SPECTRA
PROTONATION SITE OF VITAMIN-B1 AS DETERMINED FROM NATURAL-ABUNDANCE N-15 NUCLEAR MAGNETIC-RESONANCE SPECTRA
复制标题
DOI：
10.1021/ja00461a040
复制
发表时间：
1977-01-01
影响因子：
15
通讯作者：
ROBERTS, JD
中科院分区：
文献类型：
--
作者：
CAIN, AH;SULLIVAN, GR;ROBERTS, JD
天然丰度15 N NMR光谱用于确定维生素B1中质子化的位点。选择性地去耦的维生素在水，D2 O，和乙二醇允许分配的N共振，从而确定质子化的网站，这是N-1的嘧啶环的个别质子。
Natural-abundance 15N NMR spectroscopy was used to determine the site of protonation in vitamin B1. Selectively decoupling individual protons of the vitamin in water, D2O, and ethylene glycol permitted assignment of the N resonances and thence the determination of the site of protonation, which was N-1 of the pyrimidine ring.