Vaginal changes and sexuality in women with a history of cervical cancer
Vaginal changes and sexuality in women with a history of cervical cancer
复制标题
DOI：
10.1056/nejm199905063401802
复制
发表时间：
1999-05-06
影响因子：
158.5
通讯作者：
Steineck, G
中科院分区：
文献类型：
--
作者：
Bergmark, K;Åvall-Lundqvist, E;Steineck, G
背景 对于患有宫颈癌的女性，治疗会导致阴道解剖结构和功能发生变化。这些变化对性功能的影响以及它们对女性造成的困扰程度（如果有的话）尚不清楚。 方法 在 1996 年和 1997 年，我们试图联系 332 名有早期宫颈癌病史的女性（年龄范围为 26 至 80 岁），并于 1991 和 1992 年在瑞典妇科肿瘤科的七个科室接受过治疗，并询问 489 名没有癌症病史的女性（对照）。让她们回答有关阴道变化和性功能的匿名问卷。结果 我们收到了 256 名有宫颈癌病史的女性和 350 名对照者填写的问卷。 247 名有癌症病史的女性中共有 167 名（68%）和 330 名对照者中的 236 名（72%）报告说她们有定期的阴道性交。 26% 的癌症女性和 11% 的对照组报告性交时阴道润滑不足，26% 的癌症女性和 3% 的对照组报告阴道较短，23% 的癌症女性和 4% 的对照组报告阴道弹性不足。 26% 的癌症女性表示由于阴道变化而感到中度或严重的痛苦，而对照组女性中这一比例为 8%。性交困难在患有宫颈癌的女性中也更常见。两组的性高潮频率和性高潮快感相似。在患有宫颈癌的女性中，所接受的治疗类型对特定阴道变化的发生率几乎没有影响（如果有的话）。结论接受过宫颈癌治疗的女性会出现持续的阴道变化，这些变化会影响性活动并导致相当大的痛苦。 （N Engl J Med 1999；340：1383-9。）(C) 1999，马萨诸塞州医学会。
Background In women with cervical cancer, treatment causes changes in vaginal anatomy and function. The effect of these changes on sexual function and the extent, if any, to which they distress women are not known.Methods In 1996 and 1997, we attempted to contact 332 women with a history of early-stage cervical cancer (age range, 26 to 80 years) who had been treated in 1991 and 1992 at the seven departments of gynecological oncology in Sweden and 489 women without a history of cancer (controls) to ask them to answer an anonymous questionnaire about vaginal changes and sexual function.Results We received completed questionnaires from 256 of the women with a history of cervical cancer and 350 of the controls. A total of 167 of 247 women with a history of cancer (68 percent) and 236 of 330 controls (72 percent) reported that they had regular vaginal intercourse. Twenty-six percent of the women who had cancer and 11 percent of the controls reported insufficient vaginal lubrication for sexual intercourse, 26 percent of the women who had cancer and 3 percent of the controls reported a short vagina, and 23 percent of the women who had cancer and 4 percent of the controls reported an insufficiently elastic vagina. Twenty-six percent of the women who had cancer reported moderate or much distress due to vaginal changes, as compared with 8 percent of the women in the control group. Dyspareunia was also more common among the women who had cervical cancer. The frequency of orgasms and orgasmic pleasure was similar in the two groups. Among the women who had cervical cancer, the type of treatment received had little if any effect on the prevalence of specific vaginal changes.Conclusions Women who have been treated for cervical cancer have persistent vaginal changes that compromise sexual activity and result in considerable distress. (N Engl J Med 1999;340:1383-9.) (C) 1999, Massachusetts Medical Society.