JUVENILE DIABETES-MELLITUS AND SERUM-LIPIDS AND LIPOPROTEIN LEVELS
JUVENILE DIABETES-MELLITUS AND SERUM-LIPIDS AND LIPOPROTEIN LEVELS
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DOI：
10.1001/archpedi.1976.02120110075010
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发表时间：
1976-01-01
影响因子：
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通讯作者：
GLASGOW, AM
中科院分区：
文献类型：
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作者：
CHASE, HP;GLASGOW, AM
本文测定了40例糖尿病患儿和对照组的血清胆固醇、甘油三酯和脂蛋白水平。糖尿病儿童的平均胆固醇水平（205 . ±. 78毫克/分升）在统计学上高于对照组（155 . ±. 27 mg/dl），平均甘油三酯水平也是如此（120 ± 1.5mg/dl）。63对85 +-。23毫克/分升）。8例糖尿病儿童有高胆固醇血症，5例有高胆固醇血症，9例合并高胆固醇血症和高胆固醇血症。与对照组儿童相比，糖尿病儿童的低密度脂蛋白水平在统计学上更高，而高密度脂蛋白水平在统计学上更低。尿糖溢出增加与血清甘油三酯水平升高相关，提示甘油三酯水平升高可能与糖尿病控制相关。由于高脂血症与冠心病（CHD）和糖尿病与CHD之间存在已知的相关性，本研究的结果表明，所有青少年糖尿病儿童应每年进行血脂分析。
Cholesterol, triglyceride and lipoprotein levels were determined in serum from 40 children with diabetes and from controls. Mean cholesterol levels in the children with diabetes (205 .+-. 78 mg/dl) were statistically higher than for controls (155 .+-. 27 mg/dl), as were mean triglyceride levels (120 .+-. 63 vs. 85 .+-. 23 mg/dl). Eight of the children with diabetes had hypercholesterolemia, 5 had hypertriglyceridemia and 9 had combined hypercholesterolemia and hypertriglyceridemia. Low-density lipoprotein levels were statistically higher and high-density lipoprotein levels statistically lower for children with diabetes compared with control children. Increased urine glucose spillage correlated with higher serum triglyceride levels, suggesting that the elevated triglyceride levels may have been related to diabetes control. With the known association between hyperlipidemia and coronary heart disease (CHD) and between diabetes and CHD, the results of the present study indicate that all children with juvenile diabetes mellitus should have a serum lipid analysis annually.