Epidemiology of classic Kaposi's sarcoma, with special reference to Mediterranean population
Epidemiology of classic Kaposi's sarcoma, with special reference to Mediterranean population
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DOI：
10.1177/030089169508100502
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发表时间：
1995-09-01
期刊：
影响因子：
--
通讯作者：
Geddes, M
中科院分区：
文献类型：
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作者：
Franceschi, S;Geddes, M
长期以来一直怀疑南欧血统的个体中经典卡波西肉瘤（KS）过多，最近根据年龄标准化率进行了量化。在意大利，最显著的是在1976-84年期间的意大利南部，在艾滋病流行之前，KS发病率比美国和瑞典高2 - 3倍，比英格兰和威尔士以及澳大利亚高10倍。在以色列也记录了高频率的经典KS，在低风险国家，在南欧和中东出生的个体中，许多感染被怀疑在KS的病因学中起作用，包括巨细胞病毒、疟疾和最近在AIDS相关和经典KS中鉴定的疱疹家族的新病毒，本审查涉及有关KS在地中海的流行病学数据，并强调有机会联合收割机的KS在艾滋病以及非艾滋病患者的研究，以阐明这种不再罕见的疾病。
An excess of classic Kaposi's sarcoma (KS) in individuals of southern European ancestry has long been suspected and recently quantified in terms of age-standardized rates, In Italy and most notably in southern Italy for the period 1976-84, prior to the AIDS epidemic, KS incidence rates were two-to-three-fold higher than in the United States and Sweden and many ten-fold higher than in England and Wales and Australia, A high frequency of classic KS has also been documented in Israel and, in low-risk countries, in individuals born in southern Europe and the Middle East, Many infections have been suspected to play a role in the etiology of KS, including cytomegalovirus, malaria and, most recently, a new virus of the herpes family, identified in AIDS-associated and classic KS, The present review deals with epidemiologic data concerning KS in the Mediterranean and stresses the opportunity to combine the study of KS in AIDS as well as non-AIDS patients in order to shed light on this no longer rare disease.