DONOR-ACCEPTOR CHIRAL CENTRIFUGAL PARTITION CHROMATOGRAPHY - COMPLETE RESOLUTION OF 2 PAIRS OF AMINO-ACID DERIVATIVES WITH A CHIRAL-II DONOR SELECTOR
DONOR-ACCEPTOR CHIRAL CENTRIFUGAL PARTITION CHROMATOGRAPHY - COMPLETE RESOLUTION OF 2 PAIRS OF AMINO-ACID DERIVATIVES WITH A CHIRAL-II DONOR SELECTOR
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DOI：
10.1080/10826079408013481
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发表时间：
1994-01-01
期刊：
影响因子：
--
通讯作者：
LEGOFFIC, F
中科院分区：
文献类型：
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作者：
OLIVEROS, L;PUERTOLAS, PF;LEGOFFIC, F
两种外消旋化合物，即N-(3,5-二硝基苯甲酰基)-叔丁基缬氨酰胺和N-(3,5-二硝基苯甲酰基)-叔丁基亮氨酰胺，使用N-十二酰基-L-脯氨酸-3,5-二甲基苯胺作为手性选择剂，以及由庚烷、乙酸乙酯制成的双相体系，通过离心分配色谱法成功地完全拆分。甲醇和水。这为更好地理解离心分配色谱法的此类分离开辟了道路。
Two racemic compounds, namely N-(3,5-dinitrobenzoyl)-tert-butylvallnamide, and N-(3,5-dinitrobenzoyl)-tert-butylleucinamide, have been successfully completely resolved by centrifugal partition chromatography, using N-dodecanoyl-L-Proline-3,5-dimethylanilide as a chiral selector, and a biphasic system made with heptane, ethyl acetate. methanol and water. This opens the way to a better understanding of this class of separation by centrifugal partition chromatography.