In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope
In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope
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DOI：
10.1364/ol.30.002272
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发表时间：
2005-09-01
期刊：
影响因子：
3.6
通讯作者：
Schnitzer, MJ
中科院分区：
文献类型：
--
作者：
Flusberg, BA;Lung, JC;Schnitzer, MJ
我们介绍了一种紧凑型双光子荧光显微内窥镜，它由复合梯度折射率内窥镜探头、用于远程调节像面的DC测微器和用于近无失真传输超短激发脉冲的柔性光子带隙光纤组成。成像头的质量只有3.9g，提供微米级的分辨率。我们使用便携式双光子显微内窥镜对活体小鼠大脑中的海马血管进行可视化。(C)2005年美国光学学会。
We introduce a compact two-photon fluorescence microendoscope based on a compound gradient refractive index endoscope probe, a DC micrometer for remote adjustment of the image plane, and a flexible photonic bandgap fiber for near distortion-free delivery of ultrashort excitation pulses. The imaging head has a mass of only 3.9 g and provides micrometer-scale resolution. We used portable two-photon microendoscopy to visualize hippocampal blood vessels in the brains of live mice. (c) 2005 Optical Society of America.